ChemicalBook--->CAS DataBase List--->34140-59-5

34140-59-5

34140-59-5 Structure

34140-59-5 Structure
IdentificationMore
[Name]

2-(Dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate
[CAS]

34140-59-5
[Synonyms]

2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate
2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL 3,4,5-TRIMETHOXYBENZOATE MALEATE
3,4,5-trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester maleate
3,4,5-TRIMETHOXYBENZOIC ACID 2-(DIMETHYLAMINO)-2-PHENYLBUTYL ESTER MALEATE SALT
TRIMEBUTINE MALEATE
TRIMEBUTINE MALEATE SALT
TRIMEBUTIONE MALEATE
3,4,5-trimethoxy-benzoicacibeta-(dimethylamino)-beta-ethylphenethylester
debridat
dromostat
tm906
[1-ethyl-1-phenyl-2-(3,4,5-trimethoxybenzoyloxy)ethyl]dimethylammonium hydrogen maleate
TRIMEBUTINE MALEAT
TRIMEBUTINE MALEATE,2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL3.4.5-TRIMETHOXYBENZOATE MALEATE
Cerekinon
Digerent
Modulon
Polibutin
Spabucol
Transacal
[EINECS(EC#)]

251-845-9
[Molecular Formula]

C26H33NO9
[MDL Number]

MFCD00133874
[Molecular Weight]

503.54
[MOL File]

34140-59-5.mol
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

122-124°C
[storage temp. ]

2-8°C
[solubility ]

Slightly soluble in water, soluble in acetonitrile, sparingly soluble in acetone, slightly soluble in ethanol (96 per cent).
[form ]

neat
[color ]

White
[Usage]

Opioid receptor agonist. Antispasmodic
[Major Application]

pharmaceutical (small molecule)
[InChIKey]

FSRLGULMGJGKGI-BTJKTKAUSA-N
[SMILES]

C(CC)(N(C)C)(COC(=O)C1=CC(=C(OC)C(OC)=C1)OC)C1=CC=CC=C1.C(/C(=O)O)=C/C(=O)O
[CAS DataBase Reference]

34140-59-5(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H315-H335
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
[Hazard Codes ]

C
[Risk Statements ]

R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[WGK Germany ]

2
[RTECS ]

DI0360000
[Storage Class]

11 - Combustible Solids
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Potassium borohydride-->Maleic acid-->Ammonium carbonate
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Trimebutine maleate(34140-59-5) is an antispasmodic that functions as an opioid receptor agonist. Its mechanism of action involves regulating bowel movements and enhancing gastrointestinal function. Trimebutine is commonly used in the treatment of Irritable bowel syndrome. It is also used to restart the movement of the gut after abdominal surgery and to prevent intestinal blockage (paralytic ileus).
[Definition]

ChEBI: Trimebutine maleate is a trihydroxybenzoic acid.
[Side effects]

Possible side effects of trimebutine may include dry mouth, heartburn, nausea, diarrhea, constipation, drowsiness, dizziness, tiredness, indigestion, or headache. Other less frequent side effects are difficulty urinating, hearing loss, or painful breast enlargement. If any of these symptoms persist or worsen, please inform your doctor or pharmacist immediately.
[References]

https://www.drugs.com/medical-answers/trimebutine-3571789/
Trimebutine: abuse, addiction and overdose
https://myhealth.alberta.ca/Health/medications/Pages/conditions.aspx?hwid=fdb8090
Spectrum DetailBack Directory
[Spectrum Detail]

Trimebutine maleate(34140-59-5)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

34140-59-5(sigmaaldrich)
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