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34218-81-0

34218-81-0 Structure

34218-81-0 Structure
IdentificationBack Directory
[Name]

N(4), N(4), O(2')-trimethylcytidine
[CAS]

34218-81-0
[Synonyms]

N4,N4,2'-O-TriMethylcytidine
N4,N4,2’-O-Trimethylcytidine
N,N-Dimethyl-2’-O-methylcytidine
N,N-diMethyl-2'-O-Methyl- Cytidine
N(4), N(4), O(2')-trimethylcytidine
Cytidine, N,N-dimethyl-2'-O-methyl-
N,N-Dimethyl-2’-O-methylcytidine, RNA modified nucleoside m4-2C
[Molecular Formula]

C12H19N3O5
[MOL File]

34218-81-0.mol
[Molecular Weight]

285.3
Chemical PropertiesBack Directory
[Boiling point ]

470.7±55.0 °C(Predicted)
[density ]

1.44±0.1 g/cm3(Predicted)
[pka]

13.37±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

N,N-Dimethyl-2’-O-methylcytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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