| Identification | More | [Name]
Methyl sulfone | [CAS]
67-71-0 | [Synonyms]
DIMETHYL SULFONE
DIMETHYL SULPHONE
METHYL SULFONE
METHYL SULFONYL METHANE
METHYLSULPHONE
MSM
(CH3)2SO2
Methane, sulfonylbis-
Methane,sulfonylbis-
Methanesulfonylmethane
Sulfone, dimethyl-
sulfonylbis-methan
sulfonylbismethane
Sulfonylbis-methane
Sulphonylbismethane
Methyl sulfonyl mathane
dimethyl sulfone (MSM)
METHYLSULFONYLMETHANE 80 MESH
DimethylSulfone(DMS)
DimethylSulphoxideGr | [EINECS(EC#)]
200-665-9 | [Molecular Formula]
C2H6O2S | [MDL Number]
MFCD00007566 | [Molecular Weight]
94.13 | [MOL File]
67-71-0.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless crystals | [Melting point ]
107-109 °C (lit.) | [Boiling point ]
238 °C (lit.) | [density ]
1,16 g/cm3 | [refractive index ]
1.4226 | [Fp ]
290 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
150g/l | [form ]
Crystals or Crystalline Powder | [pka]
28(at 25℃) | [color ]
White | [Odor]
at 1.00?%. sulfurous burnt | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents. | [Water Solubility ]
150 g/L (20 ºC) | [Merck ]
14,3258 | [BRN ]
1737717 | [InChIKey]
HHVIBTZHLRERCL-UHFFFAOYSA-N | [LogP]
-1.074 (est) | [CAS DataBase Reference]
67-71-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Dimethyl sulfone(67-71-0) | [EPA Substance Registry System]
67-71-0(EPA Substance) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
1
| [RTECS ]
PB2785000
| [TSCA ]
Yes | [HS Code ]
29309070 | [Hazardous Substances Data]
67-71-0(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 17000 mg/kg LD50 dermal Rabbit > 5000 mg/kg |
| Questions And Answer | Back Directory | [description]
Dimethyl Sulfone (MSM) is an organic sulfur-containing compound that occurs naturally in a variety of fruits, vegetables, grains, and animals including humans. a white, odorless, slightly bitter-tasting crystalline substance containing 34-percent elemental sulfur, MSM is a normal oxidative metabolite product of dimethyl sulfoxide (DMSO). Cow’s milk is the most abundant source of MSM, containing approximately 3.3 parts per million (ppm). Other foods containing MSM are coffee (1.6 ppm), tomatoes (trace to 0.86 ppm), tea (0.3 ppm), Swiss chard (0.05-0.18 ppm), beer (0.18 ppm), corn (up to 0.11 ppm), and alfalfa (0.07 ppm).MSM has been isolated from plants such as Equisetum arvense, also known as horsetail.
Dimethyl Sulfone has the ability to enhance the body to produce insulin, while it can promote carbohydrate metabolism. It is essential for the synthesis of human collagen. It can not only promote wound healing, but also contribute for metabolic and neurological health requirement of vitamin B and vitamin C, biotin synthesis and activation, so it is known as "naturally beautiful carbon material". Dimethyl Sulfone exists in human skin, hair, nails, bones, muscles and various organs. Once people who are lack of it will get health disorders or diseases. It is the main substance for people to maintain the balance of biological sulfur. It has therapeutic value and healthcare function for people. It is an essential drug for human survial and health protection.
| [application]
- Dimethyl sulfone can eliminate the virus, enhance blood circulation, soften tissue, relieve pain, strengthen sinews and bones, calm the spirit, enhance physical strength, maintain skin, make beauty salons, treat the arthritis, oral ulcers, asthma and constipation, dredge the blood vessels, Clear gastrointestinal toxins.
- Dimethyl sulfone can be used as food and feed additives to supplement the organic sulfur nutrients for humans, pets and livestock.
- For external use, it can make the skin smooth, supple muscles, and reduce pigmentation. Recently, it surges in the amount as the cosmetic additives.
- In medicine, it has a good analgesic, it can promote wound healing and others.
- Dimethyl sulfone is a good penetrant in medicines production.
| [Purification methods]
Using different purification methods, the products contained different impurities. in the finished product is different purification methods are also different. In general, it is decolored by active carbon, demineralized by ion exchange, and then recrystallized the solvent, dried by vacuum. After that, it is sieved and added an antistatic agent and a slip agent, in order to meet the export requirements. There is no national or ministerial standards. Currently, the countries in the world continue to enforce corporate standards or contract specifications.
| [Chemical properties]
white needle-like crystals. Melting point 109 ℃, boiling point 238 ℃, relative density 1.1702 (110/0 ℃), refractive index 1.4226, flash point 143 ℃. Soluble in water, ethanol, benzene, methanol and acetone, slightly soluble in ether and chloroform. Stink.
| [Uses]
Use as high temperature solvent inorganic and organic substances, organic chemical raw materials, food additives and health products raw materials, also used as gas chromatography stationary phase (maximum use temperature 30 ℃, acetone as solvent) and analytical reagents.
| [chemical synthesis]
Dimethyl sulfone is obtained by oxidizing methyl sulfone using nitric acid as oxidation. Methyl sulfone was oxidized at 140-145 ℃ by nitric oxide. After completion of the reaction, It was cooled and filtered to give white needles crude. Then vacuum distillation, collecting 138-145 ℃ (98.42kPa) distillate products which are the finished goods.
|
| Hazard Information | Back Directory | [Definition]
ChEBI: Sulfonyldimethane is a sulfone. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 91, p. 3992, 1969 DOI: 10.1021/ja01042a075 | [General Description]
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com | [storage]
Store at -20°C |
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