ChemicalBook--->CAS DataBase List--->342631-41-8

342631-41-8

342631-41-8 Structure

342631-41-8 Structure
IdentificationBack Directory
[Name]

Tenofovir Related Compound 1
[CAS]

342631-41-8
[Synonyms]

TAF-IM-D1
TAF Impurity A
TAF Impurity 4
Tenofovir alafenamide-5
enofovir Related Compound 1
Tenofovir related Impurity 2
Tenofovir Related Compound 1
Tenofovir Alafenamide Impurity A
Tenofovir Alafenamide Impurity 1
6-amido-9-[(2R)-2-(diphenyl phosphoryl methoxy)Propyl]purine
diphenyl (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Tenofovir impurity 28/6-amido-9-[(2R)-2-(diphenyl phosphoryl methoxy)Propyl]purine
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, diphenyl ester (9CI)
[Molecular Formula]

C21H22N5O4P
[MDL Number]

MFCD29919180
[MOL File]

342631-41-8.mol
[Molecular Weight]

439.4
Chemical PropertiesBack Directory
[Boiling point ]

636.3±65.0 °C(Predicted)
[density ]

1.39±0.1 g/cm3(Predicted)
[solubility ]

Chloroform (Slightly, Sonicated), Methanol (Slightly)
[form ]

Solid
[pka]

4.21±0.10(Predicted)
[color ]

White to Pale Beige
[InChIKey]

XWTDSRIRFPGRAW-MRXNPFEDSA-N
[SMILES]

C(P(=O)(OC1=CC=CC=C1)OC1=CC=CC=C1)O[C@H](C)CN1C2C(N=C1)=C(N)N=CN=2
Hazard InformationBack Directory
[Uses]

(R)-Diphenyl (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate is a reagent for the synthesis of amidate prodrugs of PMEA and PMPA. Also functions as a reagent in the preparation of tenofovir alafenamide fumarate impurity.
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