ChemicalBook--->CAS DataBase List--->379270-38-9

379270-38-9

379270-38-9 Structure

379270-38-9 Structure
IdentificationBack Directory
[Name]

Tenofovir alafenamide fumarate
[CAS]

379270-38-9
[Synonyms]

vemlidy
GS-7340 (fuMarate)
Tenofovir alafenamide-19
tenofovir alafenamide fumarate (TAF)
Tenofovir alafenamide fumarate (GS-7340)
Tenofovir alafenamide : fumarate = 1:1)
Tenofovir alafenamide fumarate (1:1 salt)
TENOFOVIR ALAFENAMIDE FUMARATE (GS-7340 FUMARATE)
L-Alanine,N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylet...
isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate fumarate
(S)-isopropyl2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoatefumarate
N-[(S)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-L-llanine 1-methylethyl ester (2E)-2-butenedioate (1:1)
L-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, (2E)-2-butenedioate (1:1)
(S)-Isopropyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate fumarate (Tenofovir Impurity)
isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate compound with isopropyl ((S)-((((R)-1-(6-amino-
GS 7340 fumarate N-[(S)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl] phenoxyphosphinyl]-L-llanine 1-methylethyl ester (2E)-2-butenedioate (1:1)
Tenofovir impurity 42/Tenofovir Alafenamide Fumarate/isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate fumarate
[EINECS(EC#)]

223-388-5
[Molecular Formula]

C25H33N6O9P
[MOL File]

379270-38-9.mol
[Molecular Weight]

592.55
Chemical PropertiesBack Directory
[Melting point ]

119.7-121.1 °C
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

DMSO:68.0(Max Conc. mg/mL);114.56(Max Conc. mM)
Ethanol:100.0(Max Conc. mg/mL);168.48(Max Conc. mM)
Water:17.5(Max Conc. mg/mL);29.48(Max Conc. mM)
[form ]

Powder
[color ]

White to off-white
[InChIKey]

MEJAFWXKUKMUIR-GQDWUREHNA-N
[SMILES]

C(/C(=O)O)=C\C(=O)O.C(N1C=NC2=C(N=CN=C12)N)[C@@H](C)OCP(=O)(N[C@@H](C)C(=O)OC(C)C)OC1C=CC=CC=1 |&1:19,26,r|
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Tenofovir Alafenamide Fumarate is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

Tenofovir alafenamide fumarate(379270-38-9)1HNMR
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