| Identification | More | [Name]
4-Methylpyrimidin-5-amine | [CAS]
3438-61-7 | [Synonyms]
5-AMINO-4-METHYLPYRIMIDINE
5-AMIO-4-METHYLPYRIMIDINE
5-Pyrimidinamine, 4-methyl-(9CI)
5-Pyrimidinamine, 4-methyl
4-Methylpyrimidin-5-amine
4-Methyl-5-pyrimidinamine | [Molecular Formula]
C5H7N3 | [MDL Number]
MFCD09038780 | [Molecular Weight]
109.129 | [MOL File]
3438-61-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
151-151.5 °C | [Boiling point ]
246.8±20.0 °C(Predicted) | [density ]
1.155±0.06 g/cm3(Predicted) | [refractive index ]
n20D 1.58 (Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [pka]
3.21±0.16(Predicted) | [Appearance]
White to yellow Solid | [InChI]
InChI=1S/C5H7N3/c1-4-5(6)2-7-3-8-4/h2-3H,6H2,1H3 | [InChIKey]
DQNDDUOCVSWTOW-UHFFFAOYSA-N | [SMILES]
C1=NC=C(N)C(C)=N1 | [CAS DataBase Reference]
3438-61-7(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
5-Amino-4-methylpyrimidine is a pharmaceutical intermediate compound. Its structural features include a methyl group and an amino group attached to the 4th and 5th positions, respectively, on the pyrimidine ring. This substance can be used in the preparation of anticancer inhibitory compounds. | [Synthesis]
When 5-amino-2,4- dichloro-6-methylpyrimidine was hydrogenated over 10% palladium-on-charcoal in the presence of excess magnesium oxide a 31 % yield of 5-amino-4-methylpyrimidine was obtained[1].
| [References]
[1] C. G. Overberger, W. J. E., Irving C. Kogon. (1954). Derivatives of 5-Amino-4-methylpyrimidine. Journal of the American Chemical Society, 76 7, 1953–1954. https://doi.org/10.1021/ja01636a069 |
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Modachem Shanghai Co., Ltd
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