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3459-18-5

3459-18-5 Structure

3459-18-5 Structure
IdentificationMore
[Name]

4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE
[CAS]

3459-18-5
[Synonyms]

4-NITROPHENYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE
(4'-NITRO)PHENYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE
4-NITROPHENYL-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE
4-NITROPHENYL-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSIDE
4-NITROPHENYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSIDE-(1,5)
4-NITROPHENYL-N-ACETYL-B-D-GLUCOSAMINIDE
4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE
GLCNAC1-B-PNP
P-NITROPHENYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE
P-NITROPHENYL ACETYL-BETA-D-GLUCOSAMINIDE
P-NITROPHENYL-BETA-D-N-ACETYL-GLUCOSAMINIDE
P-NITROPHENYL N-ACETYL-BETA-D-GLUCOSAMINIDE
PNP-BETA-D-GLCNAC
PNP N-ACETYL-BETA-D-GLUCOSAMINIDE
4'-nitrophenyl-2-acetamido-2-deoxy-beta-glucopyranoside
P-NITROPHENYL-N-ACETYL-B-D-*GLUCOSAMINID E
P-Nitrophenyl-2-Acetamido-2-Deoxy-B-D-
1-(4-Nitrophenyl)-N-acetyl-beta-D-glucosaminide
p-Nitrophenyl 2-Acetamido-2-deoxy-b-D-glucopyranoside
4-nitrophenyl 2-acetamido-2-deoxy-β-d-glucopyranoside
[EINECS(EC#)]

222-398-7
[Molecular Formula]

C14H18N2O8
[MDL Number]

MFCD00063696
[Molecular Weight]

342.3
[MOL File]

3459-18-5.mol
Chemical PropertiesBack Directory
[Appearance]

Slightly Off-White Crystalline Solid
[Melting point ]

210-212 °C
[alpha ]

-14~-18°(D/20℃) (c=0,H2O)
[Boiling point ]

477.77°C (rough estimate)
[density ]

1.3038 (rough estimate)
[refractive index ]

1.5110 (estimate)
[storage temp. ]

−20°C
[solubility ]

H2O: 5 mg/mL, clear, colorless to very faintly yellow
[form ]

Fine Powder
[pka]

12.76±0.70(Predicted)
[color ]

White to off-white
[Water Solubility ]

water: 5mg/mL, clear, colorless to very faintly yellow
[Usage]

Useful substrate for the rapid colorimetric assay of N-Acetyl-beta-glucosaminidase in human urine
[λmax]

400nm(Phosphate buffer sol.)(lit.)
[BRN ]

96193
[InChI]

InChI=1/C14H18N2O8/c1-7(18)15-11-13(20)12(19)10(6-17)24-14(11)23-9-4-2-8(3-5-9)16(21)22/h2-5,10-14,17,19-20H,6H2,1H3,(H,15,18)/t10-,11-,12-,13-,14-/s3
[InChIKey]

OMRLTNCLYHKQCK-DOSMMQPLNA-N
[SMILES]

O(C1C=CC(N(=O)=O)=CC=1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(=O)C |&1:10,12,15,17,19,r|
[CAS DataBase Reference]

3459-18-5(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
[Hazard Codes ]

Xi
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
[WGK Germany ]

3
[F ]

10-21
[HS Code ]

29329990
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

Slightly Off-White Crystalline Solid
[Uses]

4-Nitrophenyl-N-acetyl-β- D-glucosaminide is a useful substrate for the rapid colorimetric assay of N-Acetyl-beta-glucosaminidase in human urine
[Uses]

substrate for a-L-fucosidases
[Uses]

Useful substrate for the rapid colorimetric assay of N-Acetyl-beta-glucosaminidase in human urine.
[Definition]

ChEBI: An N-acetyl-beta-D-glucosaminide in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.
[Biological Activity]

4-Nitrophenyl N-acetyl-β-D-glucosaminide (NP-GlcNAc) is a widely used hexosaminidase substrate. Enzymatic action cleaves the glycosidic bond and forms 4-nitrophenolate (pNP) which is measured at 405 nm. NP-GlcNAc can also be used in combination with diethylaminoethyl-a-cyclodextrin (DEn-CD) for a rapid and accurate rate assay method for b-N-acetylglucosaminidase. The cyclodextrin derivative is used as an additive to ionize 4-nitrophenol to yellow-colored 4-nitrophenoxide at a pH near 5the pH optimum for the enzyme.
Spectrum DetailBack Directory
[Spectrum Detail]

4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE(3459-18-5)MS
4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE(3459-18-5)1HNMR
4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE(3459-18-5)IR1
4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE(3459-18-5)IR2
4-NITROPHENYL-N-ACETYL-BETA-D-GLUCOSAMINIDE(3459-18-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

4-Nitrophenyl-2-acetamido-2-deoxy-beta-D-glucopyranoside, 99%(3459-18-5)
[Sigma Aldrich]

3459-18-5(sigmaaldrich)
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