| Identification | More | [Name]
6-Hydroxy-1-tetralone | [CAS]
3470-50-6 | [Synonyms]
6-HYDROXY-1-TETRALONE
6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone, 98%
6-HYDROXY-1-TETRALONE 98.5%
6-Hydroxy-3,4-dihydronaphthalen-1(2H)-one
6-hydroxyl-1-tetralone | [Molecular Formula]
C10H10O2 | [MDL Number]
MFCD00156670 | [Molecular Weight]
162.19 | [MOL File]
3470-50-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
154-157 °C(lit.)
| [Boiling point ]
358.0±31.0 °C(Predicted) | [density ]
1.236±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Crystalline Powder | [pka]
8.22±0.20(Predicted) | [color ]
Off-white to brown | [InChI]
InChI=1S/C10H10O2/c11-8-4-5-9-7(6-8)2-1-3-10(9)12/h4-6,11H,1-3H2 | [InChIKey]
FNSQPQKPPGALFA-UHFFFAOYSA-N | [SMILES]
C1(=O)C2=C(C=C(O)C=C2)CCC1 | [CAS DataBase Reference]
3470-50-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29145090 |
| Hazard Information | Back Directory | [Chemical Properties]
gray powder | [Uses]
6-Hydroxy-1-tetralone is used as a starting material for a one-pot conversion of phenols to anilines. | [Synthesis Reference(s)]
Journal of Medicinal Chemistry, 41, p. 1068, 1998 DOI: 10.1021/jm970527v
Journal of the American Chemical Society, 99, p. 5810, 1977 DOI: 10.1021/ja00459a052 | [General Description]
6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone (6-Hydroxy-1-tetralone) can be prepared by the demethylation of 6-methoxy-3,4-dihydro-1(2H)-naphthalenone. It participates in the synthesis of 2-alkylamino-6-hydroxy-5-hydroxymethyl-1,2,3,4-tetrahydro-1-naphthalenols. Its pKa value has been reported to be 7.74. |
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