| Identification | Back Directory | [Name]
4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid | [CAS]
351424-20-9 | [Synonyms]
TRPM4-IN-5
TRPM4-IN-1
4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid
Benzoic acid, 4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]- | [Molecular Formula]
C15H11Cl2NO4 | [MDL Number]
MFCD01930120 | [MOL File]
351424-20-9.mol | [Molecular Weight]
340.16 |
| Hazard Information | Back Directory | [Uses]
TRPM4-IN-1 (CBA) is a potent and selective inhibitor of the cation channel TRPM4, with an IC50 of 1.5 μM. TRPM4-IN-1 can be used for the research of cardiac diseases and prostate cancer[1][2]. | [storage]
Store at -20°C | [References]
[1] Lijo Cherian Ozhathil, et al. Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. Br J Pharmacol. 2018 Jun; 175(12): 2504–2519. DOI:10.1111/bph.14220
[2] Clémence Delalande, et al. Optimizing TRPM4 inhibitors in the MHFP6 chemical space. Eur J Med Chem. 2019 Mar 15;166:167-177. DOI:10.1016/j.ejmech.2019.01.048 |
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