ChemicalBook--->CAS DataBase List--->352534-93-1

352534-93-1

352534-93-1 Structure

352534-93-1 Structure
IdentificationBack Directory
[Name]

BIS-TRIS-D19
[CAS]

352534-93-1
[Synonyms]

Bis-tris-d??
BIS-TRIS (D19, 98%)
Bis-tris-d19 98 atom % D, 98% (CP)
1,1,3,3-tetradeuterio-1,3-dideuteriooxy-2-[dideuterio(deuteriooxy)methyl]-N,N-bis(1,1,2,2-tetradeuterio-2-deuteriooxyethyl)propan-2-amine
[Molecular Formula]

C8D19NO5
[MDL Number]

MFCD07784366
[MOL File]

352534-93-1.mol
[Molecular Weight]

228.356
Chemical PropertiesBack Directory
[Melting point ]

104°C (lit.)
[form ]

solid
[InChI]

1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2/i1D2,2D2,3D2,4D2,5D2,6D2,7D2,10D,11D,12D,13D,14D
[InChIKey]

OWMVSZAMULFTJU-ZMHMTVDGSA-N
[SMILES]

[2H]OC([2H])([2H])C([2H])([2H])N(C([2H])([2H])C([2H])([2H])O[2H])C(C([2H])([2H])O[2H])(C([2H])([2H])O[2H])C([2H])([2H])O[2H]
[CAS Number Unlabeled]

6976-37-0
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Dam. 1
Hazard InformationBack Directory
[Uses]

Bis-Tris-d19 is the deuterium labeled Bis-Tris[1]. Bis-Tris is a commonly used buffer[2].
[References]

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Oh, Soon Jin, et al. Structure and phosphodiesterase activity of Bis-Tris coordinated lanthanide(III) complexes.
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