ChemicalBook--->CAS DataBase List--->359010-69-8

359010-69-8

359010-69-8 Structure

359010-69-8 Structure
IdentificationBack Directory
[Name]

ROS Probe, HPF
[CAS]

359010-69-8
[Synonyms]

HPF(solution)
ROS Probe, HPF
3'-hydroxy-6'-(4-hydroxyphenoxy)spiro[2-benzofuran-3,9'-xanthene]-1-one
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3'-hydroxy-6'-(4-hydroxyphenoxy)-
[Molecular Formula]

C26H16O6
[MDL Number]

MFCD08062222
[MOL File]

359010-69-8.mol
[Molecular Weight]

424.4
Chemical PropertiesBack Directory
[Boiling point ]

674.7±55.0 °C(Predicted)
[density ]

1.56±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C, protect from light
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:8): .15 mg/ml
[form ]

Pale yellow.
[pka]

9.58±0.20(Predicted)
[color ]

Colorless to light yellow
[InChI]

InChI=1S/C26H16O6/c27-15-5-8-17(9-6-15)30-18-10-12-22-24(14-18)31-23-13-16(28)7-11-21(23)26(22)20-4-2-1-3-19(20)25(29)32-26/h1-14,27-28H
[InChIKey]

NPOSMYDPUKBGQL-UHFFFAOYSA-N
[SMILES]

C12(C3=C(C=C(OC4=CC=C(O)C=C4)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC=C1)C(=O)O2
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
Hazard InformationBack Directory
[Uses]

ROS Probe, HPF is a cell-permeable, photo-stable hydroxyphenyl-substituted fluorescein compound.
[Definition]

ChEBI: HPF is a member of xanthenes.
[in vivo]

The Hydroxyphenyl Fluorescein (HPF) probe (15 μl, 25 μM) is given intratesticularly in anaesthetized mice 20 min before IR (ionizing radiation). The accumulation of OH by the fluorescence signal emitted by the oxidized form of HPF is assessed[3].

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