| Identification | Back Directory | [Name]
Vicenin -1 | [CAS]
35927-38-9 | [Synonyms]
Vicenin -1
6-C-Xylosyl-8-C-glucosylapigenin
4',5,7-Trihydroxy-6-xylosyl-8-glucosylflavone
6-C-beta-D-Xylopyranosyl-8-C-beta-D-glucopyranosylapigenin
4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-β-D-xylopyranosyl-
8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-beta-D-xylopyranosyl-4H-1-benzopyran-4-one | [Molecular Formula]
C26H28O14 | [MOL File]
35927-38-9.mol | [Molecular Weight]
564.5 |
| Chemical Properties | Back Directory | [Melting point ]
230 °C (decomp) | [Boiling point ]
935.0±65.0 °C(Predicted) | [density ]
1.766±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
5.70±0.40(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
Vicenin 1 is a C-glycosylflavone that has an inhibitory effect on angiotensin-converting enzyme (ACE)(IC50=52.50 μM)[1]. | [Biological Activity]
Vicenin 1 is a glycosyl flavonoid isolated from the aerial part of A. chinensis. It has inhibitory effect on angiotensin-converting enzyme (ACE) (IC50=52.50 μM). | [in vitro]
The target-isolated C-glycosylflavone (Vicenin 1) is evaluated for inhibitory activities. It embodies effective ACE inhibitory activities with an IC 50 value of 52.50 μM. The tested compound 3 (Vicenin 1) shows activity via the generation of chelate complexes within the active center of ACE. | [target]
| [storage]
Store at -20°C | [References]
[1] Zhang YQ, et al. Bioassay-guided preparative separation of angiotensin-converting enzyme inhibitory C-flavone glycosides from Desmodium styracifolium by recycling complexation high-speed counter-current chromatography. J Pharm Biomed Anal. 2015 Ja DOI:10.1016/j.jpba.2014.09.027 |
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