| Identification | More | [Name]
1,3-Diaminoguanidine monohydrochloride | [CAS]
36062-19-8 | [Synonyms]
1,3-DIAMINOGUANANIDINE HYDROCHLORIDE
1,3-DIAMINOGUANIDINE HYDROCHLORIDE
1,3-DIAMINOGUANIDINE MONOHYDROCHLORIDE
DIAMINO GUANIDINE HYDROCHLORIDE
N,N'-1,3-DIAMINOGUANANIDINE MONOCHLORIDE
N,N'-1,3-DIAMINOGUANIDINE MONOCHLORIDE
N,N'-DIAMINOGUANIDINE
N,N'-DIAMINOGUANIDINE HYDROCHLORIDE
N,N'-DIAMINOGUANIDINE MONOHYDROCHLORIDE
1,3-Diaminoguanidine HCL
N,N'-1,3-Diaminoguananidine HCl
Diamino
N,N'-Diaminoguandine
N,N'-Diaminoguanidine monohydrochloride, 98+%
N,N'-Diaminoguanidine monohydrochloride 98%
(E)-HYDRAZINECARBOHYDRAZONAMIDE HYDROCHLORIDE | [EINECS(EC#)]
252-854-0 | [Molecular Formula]
CH8ClN5 | [MDL Number]
MFCD00012948 | [Molecular Weight]
125.56 | [MOL File]
36062-19-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light beige granular powder | [Melting point ]
180-182 °C (dec.)(lit.)
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
water: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow | [form ]
Granular Powder | [color ]
White to light beige | [Water Solubility ]
very faint turbidity | [Sensitive ]
Hygroscopic | [BRN ]
3556702 | [InChI]
InChI=1S/CH7N5.ClH/c2-1(5-3)6-4;/h3-4H2,(H3,2,5,6);1H | [InChIKey]
HAZRIBSLCUYMQP-UHFFFAOYSA-N | [SMILES]
C(=N)(NN)NN.Cl | [CAS DataBase Reference]
36062-19-8(CAS DataBase Reference) |
| Questions And Answer | Back Directory | [Preparation]
(1) Add guanidine hydrochloride (1 kg) and water (4 kg) to the reactor and stir until the guanidine hydrochloride is completely dissolved. Then add toluene (1.6 kg, with a mass ratio of 1:0.4 to water), and then slowly add hydrazine hydrate (1.05 kg, with a molar ratio of 1:2.0 to guanidine hydrochloride) at a dropping rate of 2.25 kg/h. After the addition is complete, react at 60°C for 10 h. Adjust the pH to 2.5 with hydrochloric acid, let stand, and separate the layers. Take the aqueous layer and distill to concentrate it until a trace amount of precipitate appears in the aqueous layer, obtaining a concentrated solution of about 2.5 kg. During the reaction, the tail gas is passed into a tail gas absorption device. The byproduct ammonia gas generated during the reaction is absorbed by a three-stage acid solution to obtain an ammonium salt solution. The acid solutions are, in order: 85% phosphoric acid aqueous solution, 50% phosphoric acid aqueous solution, and 30% phosphoric acid aqueous solution; (2) The concentrated solution was added to the high-level tank of the reactor. Anhydrous ethanol (10 kg) was added to the reactor, and the concentrated solution was added dropwise at a rate of 3 kg/h while stirring. Crystals precipitated, and after standing for 30 min, they were filtered. The crystals were washed three times with 5.0 kg of cold water and dried to obtain 1.288 kg of white target product. The total yield was 98.0%, and the purity was 99.5% as determined by HPLC. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [REACH Registrations]
Active | [HS Code ]
29212900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light beige granular powder | [Uses]
N,N''-Diaminoguanidine Monohydrochloride is an analyte for HPLC. It also functions as an intermediate for the synthesis of energetic salts or materials based on dinitroguanidine. | [General Description]
1,3-Diaminoguanidine monohydrochloride undergoes condensation reaction with:
- 4-isothiocyanato-4-methylpentane-2-one to yield condensed pyrimidines
- various aldehydes and ketones to yield bis guanidine derivatives
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