| Identification | Back Directory | [Name]
TRAMADOL HYDROCHLORIDE | [CAS]
36282-47-0 | [Synonyms]
Radol
Tadol
Zydol
Tramed
Tramol
Tridol
Ultram
Trabar
Tradol
Mabron
Adamon
Dolana
Omnidol
PoltraM
Melanate
Tradonal
Tramadex
Tramagit
Tramazac
Zumatran
NIH 10969
Bellatram
Contramal
Tramagetic
Tradol-Puren
TRAMODOL HCL
AURORA KA-863
Tramadol hydrocloride
Tramadol hydrochloride
CIS-TRAMADOL HYDROCHLORIDE
TraMadol hydrochloride USP
Tramadol hydrochloride CRS
O-DESMETHYL-CIS-TRAMADOL HCL
Tramadol Hydrochloride (100 mg)
TRAMADOL HYDROCHLORIDE USP/EP/BP
Tramadol hydrochloride - EP grade
cis-Tramadol (hydrochloride) (CRM)
(22204-88-2) tramadol hydrochloride
TraMadol Hydrochloride (1.0 Mg/ML in Methanol)
(+/-)-CIS-2-(DIMETHYLAMINOMETHYL)-1-(3-METHOXYPHENYL)CYCLOHEXANOL HYDROCHLORIDE
Cis (+) (2-(Dimethyl amino methyl)-1-(3-Methoxy phenyl) cyclohexanol monohydride
(1RS,2RS)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanolhydrochloride
Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, hydrochloride, cis-
trans-(+-)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-olhydrochlorid
trans-(±)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol hydrochloride
Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, hydrochloride, cis-(+-)-
Cyclohexanol, 2-(dimethylamino)methyl-1-(3-methoxyphenyl)-, hydrochloride, (1R,2R)-rel-
Cyclohexanol,2-[(diMethylaMino)Methyl]-1-(3-Methoxyphenyl)-, hydrochloride (1:1),(1R,2R)-rel-
Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, hydrochloride, (1R,2R)-rel- (9CI)
Tramadol HydrochlorideQ: What is
Tramadol Hydrochloride Q: What is the CAS Number of
Tramadol Hydrochloride Q: What is the storage condition of
Tramadol Hydrochloride Q: What are the applications of
Tramadol Hydrochloride | [EINECS(EC#)]
252-950-2 | [Molecular Formula]
C16H26ClNO2 | [MDL Number]
MFCD00798507 | [MOL File]
36282-47-0.mol | [Molecular Weight]
299.84 |
| Chemical Properties | Back Directory | [Melting point ]
178-181 °C | [storage temp. ]
2-8°C | [solubility ]
Freely soluble in water and in methanol, very slightly soluble in acetone. | [form ]
solid | [color ]
white to off-white |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
22-51/53 | [Safety Statements ]
61 | [RIDADR ]
UN 2811 6.1/PG 3 | [WGK Germany ]
2 | [HS Code ]
2922504500 | [Toxicity]
mouse,LD50,intravenous,61700ug/kg (61.7mg/kg),Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 114, 1978. |
| Hazard Information | Back Directory | [Description]
cis-Tramadol (hydrochloride) (CRM) (Item No. ISO60149) is a certified reference material categorized as an opioid. cis-Tramadol is regulated as a Schedule IV compound in the United States. cis-Tramadol (hydrochloride) (CRM) (Item No. ISO60149) is provided as a DEA exempt preparation. This product is intended for research and forensic applications. | [Description]
cis-Tramadol (Item No. 15919) is an analytical reference material categorized as an opioid. cis-Tramadol is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications. | [Chemical Properties]
White Solid | [Uses]
An analgesic. | [Uses]
cis-Tramadol is an analgesic that activates the μ-opioid receptor (IC50 = 7.6 μM). It also inhibits serotonin and norepinephrine reuptake and blocks voltage-gated sodium channels. This product is intended for forensic and research applications.[Cayman Chemical] | [Definition]
ChEBI:(R,R)-tramadol hydrochloride is a hydrochloride resulting from the reaction of (R,R)-tramadol with 1 molar equivalent of hydrogen chloride; the (R,R)-enantiomer of the racemic opioid analgesic tramadol hydrochloride, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a nicotinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist and a serotonin uptake inhibitor. It contains a (R,R)-tramadol(1+). It is an enantiomer of a (S,S)-tramadol hydrochloride. | [References]
[1] LIMING SHAO. Derivatives of tramadol for increased duration of effect[J]. Bioorganic & Medicinal Chemistry Letters, 2006, 16 3: Pages 691-694. DOI: 10.1016/j.bmcl.2005.10.024 |
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