| Identification | Back Directory | [Name]
Ginsenoside Rk3 | [CAS]
364779-15-7 | [Synonyms]
Ginsenoside Rk3
Ginsenoside Rk3 standard
β-D-Glucopyranoside, (3β,6α,12β)-3,12-dihydroxydammara-20,24-dien-6-yl | [Molecular Formula]
C36H60O8 | [MDL Number]
MFCD23379928 | [MOL File]
364779-15-7.mol | [Molecular Weight]
620.87 |
| Chemical Properties | Back Directory | [Boiling point ]
722.4±60.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
12.91±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Chemical Properties]
White powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from ginseng. | [Uses]
Ginsenoside Rk3 is isolated from the root of Panax notoginseng which exhibits high inhibitory activity against Epidermophyton floccosum, Trichophyton rubrum, and Trichophyton mentagrophytes. | [in vivo]
The inhibitory effects of Ginsenoside Rk3 (Rk3) on tumor progression are studied in vivo using a H460 xenograft model in nude mice. Compared with the control group, a significant inhibition of tumor growth (volume) is observed in the Ginsenoside Rk3-treated group. Twenty-one days after treatment initiation, tumor growth is significantly inhibited by approximately 62.99% in the mice receiving 20 mg/kg Ginsenoside Rk3, similar to the inhibitory effect observed in the 20 mg/kg Gefitinib-treated group (57.21%). Compared with the control group, tumor growth is moderately inhibited in the mice receiving 10 and 5 mg/kg Ginsenoside Rk3, with inhibition rates of 32.54% and 11.84%, respectively[2]. | [IC 50]
NF-κB: 14.24 μM (IC50, in HepG2 cells); NF-κB: 15.32 μM (IC50, in SK-Hep1 cell) | [storage]
4°C, protect from light |
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| Company Name: |
WG reagent
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| Telephone: |
13391486464 |
| Website: |
www.wgchemical.com |
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