ChemicalBook--->CAS DataBase List--->36507-30-9

36507-30-9

36507-30-9 Structure

36507-30-9 Structure
IdentificationBack Directory
[Name]

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
[CAS]

36507-30-9
[Synonyms]

C07496
GP 49-023
(11-epoxide-d10)
carbamazepineepoxide
10,11-epoxycarbamazepine
carbamazepine10,11-oxide
CARBAMAZEPINE 10,11-EPOXIDE
CarbaMazepine-10,11-epoxide-d10
Carbamazepine-10,11-epoxide solution
10,11-Epoxycarbamazepine (Metabolite)
10,11-Dihydro-10,11-epoxycarbamazepine
1aH-dibenzo[b,f]oxireno[2,3-d]azepine-6(10bH)-carboxaMide
f)oxiren(d)azepine-6-carboxamide,1a,10b-dihydro-6h-dibenz(
1a,10b-dihydro-6h-dibenz(b,f)oxiren(d)azepine-6-carboxamide
1a,10b-Dihydro-6H-dibenz[b,f]oxireno[d]azepine-6-carboxamide
6H-Dibenz[b,f]oxireno[d]azepine-6-carboxaMide,1a,10b-dihydro-
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
1a,10b-Dihdyro-6H-dibenzo[b,f]oxireno[d]azepine-6-carboxamide
10,11-Dihydro-10,11-epoxy-5H-dibenzo[b,f]azepine-5-carboxamide
1A,10BETA-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
[EINECS(EC#)]

200-659-6
[Molecular Formula]

C15H12N2O2
[MDL Number]

MFCD00467137
[MOL File]

36507-30-9.mol
[Molecular Weight]

252.27
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

204-206°C
[Boiling point ]

390.2±52.0 °C(Predicted)
[density ]

1.377±0.06 g/cm3(Predicted)
[Fp ]

9℃
[storage temp. ]

−20°C
[solubility ]

Chloroform (Slightly), DMSO (Slightly)
[form ]

neat
[pka]

13.91±0.20(Predicted)
[color ]

White
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

A metabolite of Carbamazepine (C175840). Representative lots contained 1-2% carbamazepine by HPLC.
[Uses]

A metabolite of Carbamazepine. Representative lots contained 1-2% carbamazepine by HPLC
[Definition]

ChEBI: An epoxide and metabolite of carbamazepine.
[General Description]

Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.
[Biochem/physiol Actions]

First metabolite of carbamazepine
Safety DataBack Directory
[Hazard Codes ]

Xn,N,T,F
[Risk Statements ]

22-36/37/38-51/53-39/23/24/25-23/24/25-11
[Safety Statements ]

26-36-61-45-36/37-16-7
[RIDADR ]

2811
[WGK Germany ]

3
[RTECS ]

HQ4430000
[HazardClass ]

6.1(b)
[PackingGroup ]

III
Spectrum DetailBack Directory
[Spectrum Detail]

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE(36507-30-9)1HNMR
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