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36531-26-7

36531-26-7 Structure

36531-26-7 Structure
IdentificationBack Directory
[Name]

OXANTEL
[CAS]

36531-26-7
[Synonyms]

OXANTEL
Telopar
CP-14445-16
OXANTEL USP/EP/BP
3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol
(E)-3-(2-(1,4,5,6-Tetrahydro-1-methyl-2-pyrimidinyl)vinyl)phenol
3-[(E)-2-(1,4,5,6-Tetrahydro-1-methylpyrimidin-2-yl)vinyl]phenol
Phenol, 3-[(1E)-2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl]-
[Molecular Formula]

C13H16N2O
[MDL Number]

MFCD00864531
[MOL File]

36531-26-7.mol
[Molecular Weight]

216.28
Chemical PropertiesBack Directory
[Boiling point ]

383.1±52.0 °C(Predicted)
[density ]

1.09±0.1 g/cm3(Predicted)
[pka]

9.42±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Anthelmintic.
[Definition]

ChEBI: Oxantel is a member of styrenes.
[Brand name]

Telopar (Pfizer).
[in vivo]

Oxantel (1-10 mg/kg; i.p.) displays a high activity against T. muris in vivo, with an EC50 of 4.71 mg/kg[1].
Oxantel (10 mg/kg; i.p.) exhibits a worm burden reduction (WBR) of 92.5% and worm expulsion rate (WER) of 88.4% for T. muris[1].

Animal Model:4 week-old female C57BL/10 mice and 3 week-old male[1]
Dosage:1 mg/kg, 2.5 mg/kg, 5 mg/kg, 10 mg/kg
Administration:Intraperitoneal injection
Result:Inhibited T. muris in vivo.
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