| Identification | Back Directory | [Name]
2-Fluoroisoniazide | [CAS]
369-24-4 | [Synonyms]
2-Fluoroisoniazide
2-fluoroisonicotinohydrazide
2-Fluoropyridine-4-carbohydrazide
2-fluoro-4-pyridinecarbohydrazide
2-FLUOROISONICOTINIC ACID HYDRAZIDE
4-Pyridinecarboxylicacid, 2-fluoro-, hydrazide | [Molecular Formula]
C6H6FN3O | [MDL Number]
MFCD08689558 | [MOL File]
369-24-4.mol | [Molecular Weight]
155.13 |
| Questions And Answer | Back Directory | [Application]
2-Fluoroisoniazid and para-aminosalicylic acid isoniazid have become alternative drugs, but the vast majority of doctors still consider 2-fluoroisoniazid an indispensable primary drug for the treatment of tuberculosis. It is considered a first-line anti-tuberculosis drug, along with rifampicin, ethambutol, streptomycin, and pyrazinamide. |
| Hazard Information | Back Directory | [Synthesis]
To 2000ml three-necked bottle add 1.62mol 2-fluoroisonicotinic acid, 1200g ethanol, 16.4g (0.162mol) triethylamine, stirring to lower the temperature to 0 ° C ~ 5 ° C, slowly drop 212g (1.78mol) sulfoxide chloride, dropletting is completed, controlled tem |
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