ChemicalBook--->CAS DataBase List--->37270-94-3

37270-94-3

37270-94-3 Structure

37270-94-3 Structure
IdentificationBack Directory
[Name]

HUMAN PF-4
[CAS]

37270-94-3
[Synonyms]

PF-4
CXCL4
Ironplact
HUMAN PF-4
HUMAN CXCL4
PF-4, HUMAN
Oncostatin A
HUMAN IROPLACT
PF-4 from mouse
PLATELET FACTOR 4
HUMAN ONCOSTATIN A
Antiheparin factor
PF-4 (CXCL4) human
PF-4,Human,recomrinant
RECOMBINANT HUMAN PF-4
HUMAN PLATELET FACTOR-4
PLATELET FACTOR-4, HUMAN
PLATELET FACTOR 4 (PF-4)
PF-4, HUMAN, RECOMBINANT
PLATELET FACTOR IV, HUMAN
Plateletfactor4humanplatelet95+%
Platelet Factor 4, Human Platelets
Human Platelet Factor-4 / CXCL4 ELISA Kit
Mouse Platelet Factor-4 / CXCL4 ELISA Kit
Recombinant Human CXCL4/PF4 Protein, No Tag
Recombinant Human Platelet Factor-4 (CXCL4)
Recombinant Human CXCL4/PF4 Protein, His Tag
platelet factor 4 human from fresh*platelet-rich
[MDL Number]

MFCD00131925
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

lyophilized
[color ]

white
[biological source]

mouse
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

3504009000
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

For research use only. Not for use in diagnostic procedures.
Human Platelet Factor-4 (PF4)/ CXCL4 (chemokine (C-X-C motif) ligand 4) ELISA Kit has been used to measure PF-4 / CXCL4 serum level in chronic myelomonocytic leukemia (CMML) patients.', 'Human Platelet Factor-4 / CXCL4 ELISA Kit has also been used in the measurement of platelet factor-4 in serum samples of prostate cancer and pseudoxanthoma elasticum patients.
[General Description]

Platelet factor-4 (PF-4) is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of platelets. The gene encoding this protein is localized on human chromosome 4. Recombinant human PF-4 is a 7.8kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.
[Biochem/physiol Actions]

Platelet factor-4 (PF-4) is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. This protein associates with heparin and neutralizes it. It also neutralizes various negatively charged proteoglycans.
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