| Identification | Back Directory | [Name]
EC 5.3.4.1 | [CAS]
37318-49-3 | [Synonyms]
PDI
DSBA
PDA2
PADI1
HPAD10
EC 5.3.4.1
LA16c-314G4.2
PAD1, GST tagged human
PROTEIN DISULFIDE ISOMERASE
Native Human Topoisomerase II α
Recombinant Disulfide Oxidoreductase
Anti-PDIA2 antibody produced in goat
protein disulfide isomerase from E. coli
THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA
Protein disulfide Isomerase bovine liver
Native Bovine Protein Disulfide Isomerase
CONNECTASH(TM) PROTEIN DISULFIDE-ISOMERASE
5-aminooxysulfonyl-2,4-dichlorobenzoic acid
PROTEIN DISULFIDE ISOMERASE, FROM BOVINE LIVER
protein disulfide isomerase family A, member 2
PROTEIN DISULFIDE ISOMERASE FROM E. COLI , 500 UG*
Protein Disulfide Isomerase from Human, Recombinant
Protein Disulfide Isomerase from bovine liver >95% (SDS-PAGE), >=100 units/mg protein, lyophilized powder | [Molecular Formula]
C7H5Cl2NO5S | [MDL Number]
MFCD00163364 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
lyophilized powder | [biological source]
human | [Specific Activity]
≥100units/mg protein | [InChI]
1S/C7H5Cl2NO5S/c8-4-2-5(9)6(16(13,14)15-10)1-3(4)7(11)12/h1-2H,10H2,(H,11,12) | [InChIKey]
DHUYKLYJBKXDBM-UHFFFAOYSA-N | [SMILES]
[S](=O)(=O)(ON)c1c(cc(c(c1)C(=O)O)Cl)Cl |
| Hazard Information | Back Directory | [Uses]
Protein Disulfide Isomerase from bovine liver has been used:
- to study the functional role of PDI in parasite infection and the interaction between macrophage PDI and?L. chagasi
- in the in vitro translation reaction for the generation of disulfide bonds
- in insulin-disulfide reduction assay and peptide binding assay
- as a positive control in thiol-disulfide oxidoreductase activity assay
| [General Description]
Protein disulfide isomerase (PDI) from bovine liver is a homodimer with a molecular weight of 107 kDa with the monomer corresponding to 57 kDa. The isoelectric point (pI) is approximately 4.2. The enzyme is a glycoprotein with 12% total carbohydrate content comprising of mannose, galactose, N-acetyl neuraminic acid (NANA) and 2-acetamido-2-deoxyglucose. PDI is an ubiquitous redox chaperone enzyme. It belongs to the, thioredoxin superfamily and is high conserved. | [Biochem/physiol Actions]
Protein Disulfide Isomerase (PDI) is mainly located in the endoplasmic reticulum (ER), where it assists in protein-folding and thiol-disulfide exchanges. It aids protein refolding in vitro allowing recombinant proteins to achieve their native state. |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
| Company Name: |
ACROBiosystems
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| Tel: |
13121935750 |
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https://www.acrobiosystems.cn/?utm_source=chemical book&utm_medium=cpy&utm_campaign=chemical book official web site |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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