| Identification | Back Directory | [Name]
CREATINE AMIDINOHYDROLASE | [CAS]
37340-58-2 | [Synonyms]
EC 3.5.3.3
CREATINASE
CRH,Creatinase
Creatinase/Aminidase
Creatine amidohydrolase
CREATINE AMIDINOHYDROLASE
Creatine amidohydrolase cr-t
Creatine amidinohydrolase（CRH）
creatinase from pseudomonas sp.
Creatinase recombinant, lyophil.
Creatininase recombinant, lyophil.
creatinase from actinobacillus sp.
creatinase from flavobacterium sp.
CREATINE AMIDINOHYDROLASE USP/EP/BP
Native Actinobacillus sp. Creatinase
Creatinase/Creatine Amidinohydrolase
Creatinase from E. coli, Recombinant
Native Flavobacterium sp. Creatinase
CREATINASE FROM FLAVOBACTERIUM SPECIES
creatinase from actinobacillus species
Creatinase from Pseudomonas sp., Recombinant
Native Microorganism Creatine Amidinohydrolase
creatinase from pseudomonas species:*recombinant
Creatinase/Creatine Amidinohydrolase, ≥8U/mg protein
CREATINASE FROM FLAVOBACTERIUM SP., LYOP HIL., ~10 U/MG
Creatinase from Actinobacillus sp. lyophilized powder, 20-40 units/mg protein | [EINECS(EC#)]
253-471-1 | [MDL Number]
MFCD00130875 |
| Hazard Information | Back Directory | [Description]
Creatine Amidinohydrolase (EC 3.5.3.3) is a hydrolase that catalyses the hydrolysis of creatine into creatine phosphate and urea. It appears as a white to off-white solid and plays a crucial role in the enzymatic determination of creatinine concentration. One unit is defined as the amount of enzyme that can react creatine to produce 1 μmol sarcosine per minute at 37°C and pH 5.5. | [Uses]
Creatine amidinohydrolase is a clinically important enzyme used in the determination of creatinine in blood and urine. | [General Description]
Creatinase is a homodimer that catalyzes hydrolysis of creatine. It consists of two monomer subunit and two defined domains; N and C terminal domains. C terminal fold have both the α helices and anti-parallel β sheet within two structurally similar domains. In between these two domains, there is a sulfhydryl group that acts as active site and the activity is metal independent. | [Biochem/physiol Actions]
Creatinase is a homodimer with subunit molecular weights of approximately 45 kDa. It catalyzes the hydrolysis of creatine, in the presence of H2O, to form urea and sarcosine. |
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