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VU661, a phenazine carboxamide, is a modulator of circadian rhythms to produce a period lengthening of the circadian rhythm. VU661 is a redox-active small molecule [1]. | [References]
[1] Kevin P Kelly, et al. Screen for Small-Molecule Modulators of Circadian Rhythms Reveals Phenazine as a Redox-State Modifying Clockwork Tuner. ACS Chem Biol. 2022 Jul 15;17(7):1658-1664. DOI:10.1021/acschembio.2c00240 |
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