3772-56-3

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3772-56-3 Structure

Identification	Back Directory
[Name] 14-Isopropylpodocarpa-8,11,13-triene-3β,13-diol
[CAS] 3772-56-3
[Synonyms] Totaradiol 3β-Hydroxytotarol (3β)-14-Isopropylpodocarpa-8,11,13-triene-3,13-diol 2,7-Phenanthrenediol, 1,2,3,4,4a,9,10,10a-octahydro-1,1,4a-trimethyl-8-(1-methylethyl)-, (2S,4aS,10aR)-
[Molecular Formula] C20H30O2
[MOL File] 3772-56-3.mol
[Molecular Weight] 302.45

Chemical Properties	Back Directory
[solubility ] Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ] Powder

Hazard Information	Back Directory
[Description] Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. Totaradiol exhibits cytotoxic activity against the A2780 ovarian cancer cell line.
[Uses] Totaradiol ((+)-Totaradiol; 3β-Hydroxytotarol) is a diterpene can be isolated from Thuja plicata (Cupressaceae)[1].
[target] NADPH-oxidase
[References] [1] Sharp H, et al. Totarol, totaradiol and ferruginol: three diterpenes from Thuja plicata (Cupressaceae). Biochem Syst Ecol. 2001 Feb 1;29(2):215-217. DOI:10.1016/s0305-1978(00)00047-8

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