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3772-56-3

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3772-56-3 Structure

3772-56-3 Structure
IdentificationBack Directory
[Name]

14-Isopropylpodocarpa-8,11,13-triene-3β,13-diol
[CAS]

3772-56-3
[Synonyms]

Totaradiol
3β-Hydroxytotarol
(3β)-14-Isopropylpodocarpa-8,11,13-triene-3,13-diol
2,7-Phenanthrenediol, 1,2,3,4,4a,9,10,10a-octahydro-1,1,4a-trimethyl-8-(1-methylethyl)-, (2S,4aS,10aR)-
[Molecular Formula]

C20H30O2
[MOL File]

3772-56-3.mol
[Molecular Weight]

302.45
Chemical PropertiesBack Directory
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
Hazard InformationBack Directory
[Description]

Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. Totaradiol exhibits cytotoxic activity against the A2780 ovarian cancer cell line.
[Uses]

Totaradiol ((+)-Totaradiol; 3β-Hydroxytotarol) is a diterpene can be isolated from Thuja plicata (Cupressaceae)[1].
[target]

NADPH-oxidase
[References]

[1] Sharp H, et al. Totarol, totaradiol and ferruginol: three diterpenes from Thuja plicata (Cupressaceae). Biochem Syst Ecol. 2001 Feb 1;29(2):215-217. DOI:10.1016/s0305-1978(00)00047-8
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