| Identification | Back Directory | [Name]
2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL | [CAS]
378775-98-5 | [Synonyms]
AK-IN-1
WAY-239320
TOSLAB 99449
2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL
2-((5,6-Bis(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl)amino)ethan-1-ol
Ethanol, 2-[[5,6-bis(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]amino]- | [Molecular Formula]
C22H21N3O4 | [MDL Number]
MFCD02987738 | [MOL File]
378775-98-5.mol | [Molecular Weight]
391.42 |
| Chemical Properties | Back Directory | [Boiling point ]
593.0±50.0 °C(Predicted) | [density ]
1.284±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
14.50±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
AK-IN-1 (compound 4072-2732) is an adenosine kinase (AK) inhibitor that is competitive for adenosine (Ado) but not for ATP. AK-IN-1 inhibits 86%, 87% and 89% of AK activity at concentrations of 2, 4 and 10 μM, respectively. AK-IN-1 has good potential for research in many disease areas, including ischaemia, inflammation and seizures[1]. | [References]
[1] Park J, et al. Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase. Protein J. 2007 Apr;26(3):203-12. DOI:10.1007/s10930-006-9062-z |
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