| Identification | More | [Name]
3,5-Bis(1,1-dimethylethyl)-2-hydroxy-benzaldehyde | [CAS]
37942-07-7 | [Synonyms]
3,5-bis(1,1-dimethylethyl)-2-hydroxy-benzaldehyde
3,5-DI-T-BUTYL-2-HYDROXYBENZALDEHYDE
3,5-DI-TBUTYLSALICYLALDEHYDE
3,5-DI-TERT-BUTYL-2-HYDROXYBENZALDEHYDE
3,5-DI-TERT-BUTYLSALICYLALDEHYDE
BENZALDEHYDE, 3,5-BIS(1,1-DIMETHYLETHYL)-2-HYDROXY-
3,5-di-tert-Butyl Salicylaldehtde
Ditert-butyl-2-hydroxybenzaldehyde
3,5-DI-TER-BUTYL-2-HYDROXYBENZYLALDEHYDE
3,5-DITERT-BUTYL-2-HYDROXYBENZALEDHYDE | [EINECS(EC#)]
629-676-0 | [Molecular Formula]
C15H22O2 | [MDL Number]
MFCD00191998 | [Molecular Weight]
234.33 | [MOL File]
37942-07-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
59-61 °C(lit.)
| [Boiling point ]
277.6±35.0 °C(Predicted) | [density ]
1.006±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Soluble in DMSO and methanol. | [form ]
Solid | [pka]
9.78±0.23(Predicted) | [color ]
Off-White to Light Yellow | [Sensitive ]
Air Sensitive | [BRN ]
1877810 | [InChI]
InChI=1S/C15H22O2/c1-14(2,3)11-7-10(9-16)13(17)12(8-11)15(4,5)6/h7-9,17H,1-6H3 | [InChIKey]
RRIQVLZDOZPJTH-UHFFFAOYSA-N | [SMILES]
C(=O)C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1O | [CAS DataBase Reference]
37942-07-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P264-P271-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29124990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Raw materials And Preparation Products | Back Directory | [Preparation Products]
(R)-(+)-2-Methyl-2-propanesulfinamide-->1,4,7,10,13-PENTAOXA-16-AZACYCLOOCTADECANE-->(S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINE-->2,4-di-tert-butyl-6-[(E)-(hydroxyimino)methyl]phenol-->Phenol, 2,2'-[(1R,2R)-1,2-cyclohexanediylbis(nitrilomethylidyne)]bis[4,6-bis(1,1-dimethylethyl)- |
| Hazard Information | Back Directory | [Chemical Properties]
3,5-Di-tert-butylsalicylaldehyde is white to yellow powder or chunks or crystal or crystalline powder
| [Uses]
3,5-Di-tert-butylsalicylaldehyde is a salicylaldehyde derivative with antibacterial activity used in the preparation nickel complexes. 3,5-Di-tert-butylsalicylaldehyde is structurally related to 3,5-di-t-butylcatechol (DTCAT) but is not as potent an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC).
| [Definition]
ChEBI: 3,5-di-tert-butyl-2-hydroxybenzaldehyde is a hydroxybenzaldehyde. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 59, p. 1939, 1994 DOI: 10.1021/jo00086a062
Tetrahedron, 46, p. 793, 1990 DOI: 10.1016/S0040-4020(01)81362-4
Tetrahedron Letters, 13, p. 4205, 1972 DOI: 10.1016/S0040-4039(01)94276-5 | [General Description]
3,5-Di-tert-butyl-2-hydroxybenzaldehyde undergoes condensation reaction with
- methyl-2-{N-(2′-aminoethane)}-amino-1-cyclopentenedithiocarboxylate to yield Schiff base ligand
- N,N-diethyl-2-methyl-1,4-phenylenediamine during the synthesis of copper(II) and cobalt(II) complexes of salicylaldimine
| [Synthesis]
500mL cigar-shaped bottle was added 2,4-di-tert-butylphenol 50mmol, paraformaldehyde 500mmol, sodium hydroxide 150mmol, triethylamine 100mmol, tetrahydrofuran 100mL, 90 ° C heating reflux stirring reaction, TLC tracking the reaction process, the reacti |
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