| Identification | Back Directory | [Name]
flavipucine | [CAS]
38473-18-6 | [Synonyms]
Flavipucin
flavipucine
1-Oxa-5-azaspiro[2.5]oct-6-ene-4,8-dione, 6-methyl-2-(3-methyl-1-oxobutyl)-, (2R,3R)- | [Molecular Formula]
C12H15NO4 | [MOL File]
38473-18-6.mol | [Molecular Weight]
237.25 |
| Hazard Information | Back Directory | [Uses]
Flavipucine (Flavipucin), a glutarimide antibiotic, is found in the strain of Aspergillus flavipes F-2090/7. Flavipucine has antibacterial activity against B. subtilis. Flavipucine has antiprotozoal activity. Flavipucine has cytotoxic activity against several cancer cells[1][2]. | [References]
[1] Kusakabe Y, et al. Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1390-1394. DOI:10.1016/j.bmcl.2019.03.034
[2] Boya P CA, et al. Antiprotozoal Natural Products from Endophytic Fungi Associated with Cacao and Coffee. Metabolites. 2024 Oct 25;14(11):575. DOI:10.3390/metabo14110575 |
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