ChemicalBook--->CAS DataBase List--->3852-09-3

3852-09-3

3852-09-3 Structure

3852-09-3 Structure
IdentificationMore
[Name]

Methyl 3-methoxypropionate
[CAS]

3852-09-3
[Synonyms]

3-METHOXYPROPIONIC ACID METHYL ESTER
METHYL 3-METHOXYPROPIONATE
3-methoxy-propanoicacidmethylester
3-methoxy-propanoicacimethylester
3-methoxy-propionicacimethylester
beta-methoxypropionicacid,methylester
methyl3-methoxypropanoate
methylbeta-methoxypropionate
methylesterkyseliny3-methoxypropionove
Propanoicacid,3-methoxy-,methylester
Propanoicacid,3-methoxy-,methylether
METHYL 3-METHOXYPROPIONATE, 99+%
Methylmethoxypropanoate
Methyl β-Methoxypropionate
[EINECS(EC#)]

223-358-1
[Molecular Formula]

C5H10O3
[MDL Number]

MFCD00059085
[Molecular Weight]

118.13
[MOL File]

3852-09-3.mol
Chemical PropertiesBack Directory
[Appearance]

clear colorless liquid
[Boiling point ]

142-143 °C (lit.)
[density ]

1.009 g/mL at 25 °C(lit.)
[vapor pressure ]

9.733-15.999hPa at 20-25℃
[refractive index ]

n20/D 1.402(lit.)
[Fp ]

118 °F
[storage temp. ]

Flammables area
[form ]

clear liquid
[color ]

Colorless to Almost colorless
[Specific Gravity]

1.013 (20℃)
[Water Solubility ]

428.60g/L(25 ºC)
[BRN ]

1744829
[InChI]

InChI=1S/C5H10O3/c1-7-4-3-5(6)8-2/h3-4H2,1-2H3
[InChIKey]

BDJSOPWXYLFTNW-UHFFFAOYSA-N
[SMILES]

C(OC)(=O)CCOC
[LogP]

0.1
[CAS DataBase Reference]

3852-09-3(CAS DataBase Reference)
[EPA Substance Registry System]

3852-09-3(EPA Substance)
Questions And AnswerBack Directory
[Preparation]

In a dry reaction flask, 0.2 mL of Na₂CO₃ (0.05 M aq.) was added to a solution of ethyl acrylate (0.5 mmol) and methanol (2.0 mmol). The resulting reaction mixture was stirred at room temperature for approximately 5 hours until the olefins were completely consumed. The reaction progress was monitored by thin-layer chromatography (TLC). After the reaction was complete, the reaction mixture was extracted three times with ethyl acetate (3 x 5 mL). The combined organic layers were washed with brine (10 mL) and dried over Na₂SO₄. The organic layers were filtered to remove the drying agent, and the resulting organic solvent was concentrated under vacuum. The crude product was purified by silica gel column chromatography (eluent: PE: EtOAc = 8:1) to obtain methyl 3-methoxypropionate.
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Warning
[Hazard statements ]

H226-H315-H319-H335
[Precautionary statements ]

P210-P302+P352-P305+P351+P338
[Hazard Codes ]

Xi
[Risk Statements ]

R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
[RIDADR ]

UN 3272 3/PG 3
[WGK Germany ]

3
[RTECS ]

UF5274000
[TSCA ]

TSCA listed
[REACH Registrations]

Active
[HazardClass ]

3.2
[PackingGroup ]

III
[HS Code ]

29189900
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Methyl 3-methoxypropionate(3852-09-3).msds
Hazard InformationBack Directory
[Chemical Properties]

clear colorless liquid
[Uses]

Methyl 3-methoxypropionate may be employed as acylation reagent for the lipase-catalyzed N-acylation of 1-phenylethanamine. It may be used in the synthesis of poly(2-hydroxylethyl 5-norbornene-2-carboxylate /t-butyl 5-norbornene-2-carboxylate /5-norbornene-2-carboxylic acid /maleic anhydride) resists. Lithographic performance of these resists was studied using ArF stepper.
[Synthesis Reference(s)]

Journal of the American Chemical Society, 68, p. 544, 1946 DOI: 10.1021/ja01208a003
[General Description]

Methyl 3-methoxypropionate is an ester.
Spectrum DetailBack Directory
[Spectrum Detail]

Methyl 3-methoxypropionate(3852-09-3)MS
Methyl 3-methoxypropionate(3852-09-3)1HNMR
Methyl 3-methoxypropionate(3852-09-3)13CNMR
Methyl 3-methoxypropionate(3852-09-3)IR1
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

3852-09-3(sigmaaldrich)
[TCI AMERICA]

Methyl 3-Methoxypropionate,>99.0%(GC)(3852-09-3)
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