| Identification | Back Directory | [Name]
8-HYDROXYGUANOSINE | [CAS]
3868-31-3 | [Synonyms]
8-OHG
8-OXO-G
8-OH-GUO
NSC 90393
8-Hydroxy-Gr
8-OXOGUANOSINE
8-Oxo-D-guanosine
8-HYDROXYGUANOSINE
7,8-dihydro-8-oxo-guanosin
7,8-DIHYDRO-8-OXO-GUANOSINE
Guanosine, 7,8-dihydro-8-oxo-
2-AMino-9-β-D-ribofuranosyl-purine-6,8(1H,9H)-dione
9h)-dione,2-amino-9-beta-d-ribofuranosyl-purine-8(1h
2-amino-9-beta-d-ribofuranosylpurine-6,8(1h,9h)-dione
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione | [Molecular Formula]
C10H13N5O6 | [MDL Number]
MFCD00216136 | [MOL File]
3868-31-3.mol | [Molecular Weight]
299.24 |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
232-235°C | [density ]
2.43±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) Water (Slightly, Heated,Sonicated) | [form ]
White to off-white powder. | [pka]
7.75±0.20(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro | [Uses]
It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells. | [Definition]
ChEBI: 8-Hydroxyguanosine is a purine nucleoside. | [Safety Profile]
Mutation data reported. When heated to decomposition it emits toxic vapors of NOx. |
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