| Identification | Back Directory | [Name]
Tetrahydricheilanthifolinium | [CAS]
38691-95-1 | [Synonyms]
Groenlandicine
Groenlandicine Bromide
Dehydrocheilanthifoline
Tetrahydrocheilanthifoline
Tetradehydrocheilanthifoline
Tetrahydricheilanthifolinium
Tetradehydrocheilanthiofolinium
GroenlandicineTetradehydrocheilanthifoline
11,12-Dihydro-8-methoxy-9-hydroxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium
11,12-Dihydro-9-hydroxy-8-methoxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium | [Molecular Formula]
C19H16NO4+ | [MDL Number]
MFCD22586442 | [MOL File]
38691-95-1.mol | [Molecular Weight]
322.34 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. | [Uses]
Used for content determination/identification/pharmacological experiments, etc. | [Health effects]
Groenlandicine has an anti-inflammatory, analgesic, cooling, antihypertensive, anticancer effect. | [Biological Activity]
Groenlandicine is a protoberberine alkaloid isolated from Coptis chinensis. It has moderate inhibitory effect on human recombinant aldose reductase (HRAR) with IC50 value of 154.2 μM. And Groenlandicine can induces topoisomerase I (topoisomerase I)-mediated DNA cleavage. | [target]
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