| Identification | Back Directory | [Name]
Worenine | [CAS]
38763-29-0 | [Synonyms]
Worenin
Worenine
Berberine Impurity 6
5,6-Dihydro-14-methyl-bis[1,3]benzodioxolo[5,6-a:5',6'-g]quinolizinium | [Molecular Formula]
C20H16NO4+ | [MDL Number]
MFCD30748202 | [MOL File]
38763-29-0.mol | [Molecular Weight]
334.345 |
| Hazard Information | Back Directory | [Description]
This quaternary alkaloid is present in Cop tis japonica and has been isolated as
the tetrahydro base, colourless prisms from EtOH with m.p. 2l2-3°C, oxidized
by iodine in EtOH to worenine iodide. The latter forms yellow crystals from
which the corresponding chloride may be obtained in the form of orange-yellow
prisms, m.p. 295°C (dec.).
| [Chemical Properties]
Red crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Coptis chinensis. | [Uses]
Worenine is used in the a flurophore switched probe which aids in correction of an abasic site (AP site) caused by the removal of a damaged base in DNA | [Definition]
ChEBI: Worenine is an alkaloid. | [References]
Kitasato., J. Pharm. Soc., Japan, No. 542, 48 (1927)
Kitasato., Acta Phytochimica, 3,210 (1927) |
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