| Identification | Back Directory | [Name]
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-aminophenylacetyl]amino]-3-(hydroxymethyl)-8-oxo-, (6R,7R)- (9CI) | [CAS]
3890-34-4 | [Synonyms]
Deacetylcephaloglycin
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-aminophenylacetyl]amino]-3-(hydroxymethyl)-8-oxo-, (6R,7R)- (9CI) | [Molecular Formula]
C16H17N3O5S | [MOL File]
3890-34-4.mol | [Molecular Weight]
363.39 |
| Hazard Information | Back Directory | [Description]
Deacetylcephaloglycin is an active metabolite of cephaloglycin, excreted in human urine. | [Uses]
Deacetylcephaloglycin is the active metabolite of Cephaloglycin (HY-16137). Deacetylcephaloglycin is a degradation product of Cephaloglycin that eliminates the 3-acetyl group in acidic medium and can be further degraded to Deacetylcephaloglycin lactone. Deacetylation is the rate-determining step in the degradation of Cephaloglycin to lactone[1]. | [References]
[1] Haginaka J, et al. Acidic degredation of cephaloglycin and high performance liquid chromatographic determination of deacetylcephaloglycin in human urine. J Antibiot (Tokyo). 1979 May;32(5):462-7. DOI:10.7164/antibiotics.32.462 |
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