| Identification | Back Directory | [Name]
4-β-D-Glucopyranosyloxybenzeneethanol | [CAS]
38954-02-8 | [Synonyms]
Icariside D2
4-β-D-Glucopyranosyloxybenzeneethanol
β-D-Glucopyranoside, 4-(2-hydroxyethyl)phenyl | [Molecular Formula]
C14H20O7 | [MDL Number]
MFCD29059635 | [MOL File]
38954-02-8.mol | [Molecular Weight]
300.3 |
| Hazard Information | Back Directory | [Uses]
Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis [1][2]. | [Definition]
ChEBI: Icariside D2 is a glycoside. | [References]
[1] Nguyen Thi Thu Hien, et al. Chemical Constituents of the Annona Glabra Fruit and Their Cytotoxic Activity. Pharm Biol. 2015;53(11):1602-7. DOI:10.3109/13880209.2014.993042
[2] Xue Liu, et al. Metabolic Engineering Escherichia coli for Efficient Production of Icariside D2. Biotechnol Biofuels. 2019 Nov 6;12:261. DOI:10.1186/s13068-019-1601-x
[3] Jin-YuLi, et al. Three new acylated prenylflavonol glycosides from Epimedium koreanum. Phytochemistry Letters Volume 17, September 2016, Pages 206-212. |
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