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390362-51-3

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390362-51-3 Structure

390362-51-3 Structure
IdentificationBack Directory
[Name]

Buxbodine B
[CAS]

390362-51-3
[Synonyms]

Buxbodine B
9,19-Cyclopregn-1-en-3-one, 20-(dimethylamino)-16-hydroxy-4,4,14-trimethyl-, (5α,16β,20S)-
[Molecular Formula]

C26H41NO2
[MDL Number]

MFCD20260656
[MOL File]

390362-51-3.mol
[Molecular Weight]

399.62
Chemical PropertiesBack Directory
[Boiling point ]

501.7±50.0 °C(Predicted)
[density ]

1.11±0.1 g/cm3(Predicted)
[pka]

15.10±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Buxbodine B is an inhibitor for acetylcholinesterase (AChE) with an IC50 of 50 μM. Buxbodine B can be used in research of Alzheimer's disease[1].
[IC 50]

AChE: 50 μM (IC50)
[References]

[1] Lam CW, et al., Bioactive steroidal alkaloids from Buxus macowanii Oliv. Steroids. 2015 Mar;95:73-9. DOI:10.1016/j.steroids.2014.12.002
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