| Identification | Back Directory | [Name]
5,6-Dihydro-5-oxoindolo[1,2-a]quinazoline-7-acetic acid | [CAS]
391670-48-7 | [Synonyms]
IQA
Casein Kinase II Inhibitor IX, IQA
2-(5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
5,6-Dihydro-5-oxoindolo[1,2-a]quinazoline-7-acetic acid
Indolo[1,2-a]quinazoline-7-acetic acid, 5,6-dihydro-5-oxo-
2-(5-oxo-5,6-dihydroindolo[1,2-a]quinazolin-7-yl)acetic acid
Casein Kinase II Inhibitor IX, IQA - CAS 391670-48-7 - Calbiochem | [Molecular Formula]
C17H12N2O3 | [MDL Number]
MFCD10567698 | [MOL File]
391670-48-7.mol | [Molecular Weight]
292.29 |
| Chemical Properties | Back Directory | [Boiling point ]
383.5±34.0 °C(Predicted) | [density ]
1.46 | [storage temp. ]
+2C to +8C | [solubility ]
DMSO: 10 mg/ml | [form ]
Light yellow solid | [pka]
4.32±0.10(Predicted) | [color ]
light yellow |
| Hazard Information | Back Directory | [Uses]
IQA (CGP-029482) is a potent and selective protein kinase CK2 inhibitor[1]. | [IC 50]
CK2 | [References]
[1] Liu J, et al. Cascade Reaction of Morita-Baylis-Hillman Acetates with 1,1-Enediamines or Heterocyclic Ketene Aminals: Synthesis of Highly Functionalized 2-Aminopyrroles. J Org Chem. 2019 Feb 15;84(4):1797-1807. DOI:10.1021/acs.joc.8b02594 |
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