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141223-71-4

141223-71-4 Structure

141223-71-4 Structure
IdentificationBack Directory
[Name]

BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE
[CAS]

141223-71-4
[Synonyms]

Z-VKM-AMC
Z-VAL-LYS-MET-AMC
Z-VAL-LYS-MET-MCA
CBZ-VAL-LYS-MET-AMC
Z-VAL-LYS-MET-AMC ACETATE SALT
Z-VAL-LYS-MET-MCA HYDROCHLORIDE
Fluorogenic Proteasome Substrate
PROTEASOME SUBSTRATE IV (FLUOROGENIC)
z-val-lys-met 7-amido-4-methylcoumarin
N-CBZ-VAL-LYS-MET 7-AMIDO-4-METHYLCOUMARIN
BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE
N-[(Phenylmethoxy)carbonyl]-L-valyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-methioninamide
L-Methioninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
benzyl N-[1-[[6-amino-1-[[1-[(4-methyl-2-oxochromen-7-yl)amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
[Molecular Formula]

C34H45N5O7S
[MDL Number]

MFCD01567314
[MOL File]

141223-71-4.mol
[Molecular Weight]

667.82
Chemical PropertiesBack Directory
[Boiling point ]

966.2±65.0 °C(Predicted)
[density ]

1.245±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[pka]

11.05±0.46(Predicted)
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Fluorogenic Proteasome Substrate (Z-VKM-AMC) is used to measure the peptidase activity of the 20S proteasome. Also used as a fluorogenic substrate for Alzheimer''s Disease amyloid A4-generating enzymes. AMC has an excitation maximum of 340-360nm and an emission maximum of 440-460nm.
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