ChemicalBook--->CAS DataBase List--->402616-23-3

402616-23-3

402616-23-3 Structure

402616-23-3 Structure
IdentificationBack Directory
[Name]

FTY720 (R)-Phosphate
[CAS]

402616-23-3
[Synonyms]

FTY720 (R)-Phosphate
LRFKWQGGENFBFO-LJQANCHMSA-N
FTY720 (R)-Phosphate Exclusive
1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-, 1-(dihydrogen phosphate), (2R)-
[Molecular Formula]

C19H34NO5P
[MOL File]

402616-23-3.mol
[Molecular Weight]

387.45
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Chloroform: 0.5 mg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Fingolimod Phosphate is an intermediate in sphingolipid homeostasis and a major medical target for immune system modulation. A potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. A potential new target in the treatment of auto-?immune diseases.
[Definition]

ChEBI: Fingolimod phosphate is a primary amino compound that is fingolimod in which one on the hydroxy groups has been converted into its dihydrogen phosphate derivative. It is the active metabolite of fingolimod. It has a role as an antineoplastic agent, an immunosuppressive agent and a sphingosine-1-phosphate receptor agonist. It is a monoalkyl phosphate, a primary amino compound and a primary alcohol. It is functionally related to a fingolimod.
[in vivo]

(R)-FTY 720P (intravenous bolus administration ) has no clear effect on heart rate up to a dose of 0.3mg/kg in anesthetized rats[1].

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