| Identification | Back Directory | [Name]
4-Methoxypiperidine hydrochloride | [CAS]
4045-25-4 | [Synonyms]
EOS-62183
4-Methoxypiperidine HCl
4-Methoxypiperidine hydr...
4-METHOXY-PIPERIDINE HYDROCHLORIDE
4-Methoxypiperidine Monohydrochloride
4-methoxy-1l2-piperidinehydrochloride
Piperidine, 4-methoxy-, hydrochloride (1:1) | [EINECS(EC#)]
223-742-9 | [Molecular Formula]
C6H14ClNO | [MDL Number]
MFCD06800959 | [MOL File]
4045-25-4.mol | [Molecular Weight]
151.63 |
| Chemical Properties | Back Directory | [Melting point ]
137.5-139.5 °C | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
solid | [color ]
White | [InChI]
InChI=1S/C6H13NO.ClH/c1-8-6-2-4-7-5-3-6;/h6-7H,2-5H2,1H3;1H | [InChIKey]
DMFJRRMECZFOKR-UHFFFAOYSA-N | [SMILES]
N1CCC(OC)CC1.[H]Cl |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Synthesis]
Step 3: Preparation of Intermediate 41a; To a 1,4-dioxane (5 mL) solution of Intermediate 40a (810 mg, 3.76 mmol) under stirring was slowly added a 1,4-dioxane solution (8 mL) of 4M HCl at 0 °C. The reaction mixture was kept at 0°C and stirring was continued for 2 hours. Subsequently, the reaction system was warmed up to 23 °C and the organic solvent was evaporated under reduced pressure. The resulting residue was washed with anhydrous ether and finally dried under vacuum to give Intermediate 41a (430 mg, yield > 99%) in the form of hydrochloride. | [References]
[1] Patent: US2011/92475, 2011, A1. Location in patent: Page/Page column 18
[2] Patent: WO2006/64196, 2006, A1. Location in patent: Page/Page column 138-139
[3] Patent: US2005/261291, 2005, A1. Location in patent: Page/Page column 67
[4] Patent: US6194409, 2001, B1
[5] Patent: EP1621537, 2006, A1. Location in patent: Page/Page column 52 |
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