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4051-59-6

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4051-59-6 Structure

4051-59-6 Structure
IdentificationBack Directory
[Name]

msx-130
[CAS]

4051-59-6
[Synonyms]

msx-130
MSX-130; MSX 130; MSX130
1H-Imidazole, 2,2'-(1,4-phenylene)bis[4,5-diphenyl-
[Molecular Formula]

C36H26N4
[MDL Number]

MFCD00231029
[MOL File]

4051-59-6.mol
[Molecular Weight]

514.62
Chemical PropertiesBack Directory
[solubility ]

DMSO:3.0(Max Conc. mg/mL);5.83(Max Conc. mM)
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Biological Activity]

MSX-130 is a CXCR4 antagonist. It inhibits tumor metastasis.
[in vitro]

The CXC chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization.

[target]

CXCR4

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