41060-16-6

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41060-16-6 Structure

Chemical Properties	Back Directory
[density ] 1.402
[solubility ] Soluble in chloroform and methanol;
[form ] powder
[pka] 6.81±0.40(Predicted)
[color ] Yellow
[Water Solubility ] insoluble in water

Hazard Information	Back Directory
[Uses] Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a[1].
[target] Caspase \| NO \| PGE \| IL Receptor
[References] [1] Yang B, et al. Anti-cancer, Anti-collagenase and Anti-elastase Potentials of Some Natural Derivatives: In vitro and in silico Studies. J Oleo Sci. 2023;72(5):557-570. DOI:10.5650/jos.ess22337 [2] Cui J, et al. Skullcapflavone I has a potent anti-pancreatic cancer activity by targeting miR-23a. Biofactors. 2020 Sep;46(5):821-830. DOI:10.1002/biof.1621

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