| Identification | Back Directory | [Name]
Hirsutal | [CAS]
41137-86-4 | [Synonyms]
Hirsutal
3-Heptanone, 1,7-bis(3,4-dihydroxyphenyl)-5-hydroxy-, (5S)- | [Molecular Formula]
C19H22O6 | [MDL Number]
MFCD20274780 | [MOL File]
41137-86-4.mol | [Molecular Weight]
346.37 |
| Hazard Information | Back Directory | [Uses]
Hirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC50 value of 44.11 μg/mL for microfilariae[1]. | [References]
[1] Lee MW, et al. Inhibition of cyclooxygenase-2 expression by diarylheptanoids from the bark of Alnus hirsuta var. sibirica. Biol Pharm Bull. 2000 Apr;23(4):517-8. DOI:10.1248/bpb.23.517
[2] Yadav D, et al. Antifilarial diarylheptanoids from Alnus nepalensis leaves growing in high altitude areas of Uttarakhand, India. Phytomedicine. 2013 Jan 15;20(2):124-32. DOI:10.1016/j.phymed.2012.10.017 |
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