| Identification | Back Directory | [Name]
5-N-HEPTADECYLRESORCINOL | [CAS]
41442-57-3 | [Synonyms]
5-N-HEPTADECYLRESORCINOL
5-Heptadecylbenzene-1,3-diol
5-Heptadecyl-1,3-benzenediol
5-Heptadecyl-1,3-dihydroxybenzene | [Molecular Formula]
C23H40O2 | [MDL Number]
MFCD09743627 | [MOL File]
41442-57-3.mol | [Molecular Weight]
348.56 |
| Chemical Properties | Back Directory | [Melting point ]
91-93 °C | [Boiling point ]
478.0±15.0 °C(Predicted) | [density ]
0.950±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
neat | [pka]
9.55±0.10(Predicted) | [color ]
Off-white to light yellow | [BRN ]
2287460 |
| Hazard Information | Back Directory | [Uses]
5-Heptadecylresorcinol may be used as an analytical reference standard for the quantification of the analyte in mango peels, rye grains and agricultural products using different chromatography techniques. | [Definition]
ChEBI: 5-heptadecylresorcinol is a 5-alkylresorcinol that is resorcinol which is substituted by a heptadecyl group at position 5. It is found in wheat bran. It has a role as an antineoplastic agent and a plant metabolite. | [General Description]
5-Heptadecylresorcinol belongs to the group of alk(en)ylresorcinols (ARs), exhibiting pharmacological properties such as anti-inflammatory, anti-carcinogenic and anti-microbial bioactivities. It is most commonly found in cereals such as barley, spelt, wheat, rye, ginkgo, mango peels, pulp, peas, etc. | [in vivo]
5-Heptadecylresorcinol (30 mg/kg, 150 mg/kg; po daily for 16 weeks) improves the lipid metabolism in HFD-fed ApoE?/? mice[1].
5-Heptadecylresorcinol (30 mg/kg, 150 mg/kg; po daily for 16 weeks) increases the body weight of mouse, and alleviates adipose tissue macrophage infiltration and mitochondrial dysfunction[2].
| Animal Model: | C57BL/6J mice[1][2] | | Dosage: | 30 mg/kg, 150 mg/kg | | Administration: | PO; daily for 16 weeks | | Result: | Lowered serum total cholesterol, triglyceride, VLDL-C, and LDL-C levels[1].
Reduced adipose tissue macrophage infiltration from high-fat diet induced obese C57BL/6J mice[2]. |
| [IC 50]
SIRT3 |
|
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