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420785-70-2

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420785-70-2 Structure

420785-70-2 Structure
IdentificationBack Directory
[Name]

2H-1,4-Benzoxazin-3(4H)-one, 6-[[1-[2-[(2-methyl-5-quinolinyl)oxy]ethyl]-4-piperidinyl]methyl]-
[CAS]

420785-70-2
[Synonyms]

SB649915
SB-649915
SB 649915
2H-1,4-Benzoxazin-3(4H)-one, 6-[[1-[2-[(2-methyl-5-quinolinyl)oxy]ethyl]-4-piperidinyl]methyl]-
[Molecular Formula]

C26H29N3O3
[MDL Number]

MFCD18074521
[MOL File]

420785-70-2.mol
[Molecular Weight]

431.53
Chemical PropertiesBack Directory
[Melting point ]

207-208 °C
[Boiling point ]

648.3±55.0 °C(Predicted)
[density ]

1.212±0.06 g/cm3(Predicted)
[pka]

12.72±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

SB-649915 is a potent 5-HT1A/1B autoreceptor antagonist, with the pKi values of 8.6, 8.0, respectively and 5-HT reuptake inhibitor in native tissue systems and palys an important role in antidepressant research[1].
[References]

[1] Claire Scott, et al. SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue. Eur J Pharmacol. 2006 Apr 24;536(1-2):54-61. DOI:10.1016/j.ejphar.2006.02.042
420785-70-2 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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