| Identification | Back Directory | [Name]
2-MORPHOLINOBENZOIC ACID | [CAS]
42106-48-9 | [Synonyms]
AKOS BB-8942
BUTTPARK 98\12-69
CHEMBRDG-BB 4006143
RARECHEM AL BO 2105
2-MORPHOLINOBENZOIC ACID
2-(4-Morpholino)benzoic acid
2-(4-Morpholinyl)benzoic Acid
2-Morpholinobenzoic acid ,97%
2-(MORPHOLIN-4-YL)BENZOIC ACID
Benzoic acid, 2-(4-morpholinyl)-
2-morpholin-4-ylbenzoic acid(SALTDATA: FREE) | [Molecular Formula]
C11H13NO3 | [MDL Number]
MFCD00527976 | [MOL File]
42106-48-9.mol | [Molecular Weight]
207.23 |
| Chemical Properties | Back Directory | [Melting point ]
157 °C | [Boiling point ]
387.5±37.0 °C(Predicted) | [density ]
1.253±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
2.67±0.36(Predicted) | [Appearance]
Light yellow to light brown Solid | [CAS DataBase Reference]
42106-48-9 |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
2-Morpholinobenzoic Acid is used in the preparation of amino acids as inhibitors of αvβ integrin and for treating fibrosis. | [Synthesis]
The general procedure for the synthesis of 2-(4-morpholinyl)benzoic acid from ethyl 2-morpholinobenzoate was as follows: referring to the method of Example 1e, ethyl 2-(morpholin-4-yl)-benzoate was reacted with 2 molar equivalents of sodium hydroxide in methanol solution. After completion of the reaction, the target product 2-(4-morpholinyl)benzoic acid was obtained after post-processing in 90% yield of the theoretical value. The Rf value of the product was 0.75 (silica gel plate; unfolding agent ratio dichloromethane/ethanol/ammonia = 8:4:0.2). | [References]
[1] Patent: US2003/162788, 2003, A1
[2] Patent: US2003/73836, 2003, A1
[3] Patent: EP1147095, 2004, B1. Location in patent: Page 68 |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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