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422508-46-1

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422508-46-1 Structure

422508-46-1 Structure
IdentificationBack Directory
[Name]

PU-24FCl
[CAS]

422508-46-1
[Synonyms]

PU-24FCl
8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-2-fluoro-9-pent-4-ynylpurin-6-amine
[Molecular Formula]

C20H21ClFN5O3
[MDL Number]

MFCD20527249
[MOL File]

422508-46-1.mol
[Molecular Weight]

433.86
Chemical PropertiesBack Directory
[Boiling point ]

668.0±65.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[pka]

1.68±0.10(Predicted)
Hazard InformationBack Directory
[Description]

PU24FCl is a specific inhibitor of tumor Hsp90.
[Uses]

PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue[1].
[IC 50]

HSP90
[References]

[1] Vilenchik M, et, al. Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90. Chem Biol. 2004 Jun;11(6):787-97. DOI:10.1016/j.chembiol.2004.04.008
422508-46-1 suppliers list
Company Name: TargetMol Chemicals Inc.
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Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
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Company Name: TargetMol Chemicals Inc.  
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Website: https://www.targetmol.cn/
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