| Identification | Back Directory | [Name]
ACACETIN-7-GLUCOSIDE | [CAS]
4291-60-5 | [Synonyms]
TILIANIN
Astroside
Moldavoside
leptomerine
ACACETIN-7-GLUCOSIDE
Acacetin 7-O-glucoside
ACACETIN-7-GLUCOSIDE USP/EP/BP
Apigenin-7-O-beta-D-glucopyranoside-4'-O-methyl ether
7-(β-D-Glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)- | [Molecular Formula]
C22H22O10 | [MDL Number]
MFCD00238695 | [MOL File]
4291-60-5.mol | [Molecular Weight]
446.4 |
| Chemical Properties | Back Directory | [Melting point ]
260-262℃ | [Boiling point ]
754.9±60.0 °C(Predicted) | [density ]
1.545±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO | [form ]
powder | [pka]
6.11±0.40(Predicted) | [color ]
White-yellowish | [InChIKey]
NLZCOTZRUWYPTP-KWEUGPCZNA-N | [SMILES]
C1(C2=CC=C(OC)C=C2)OC2=C(C(=CC(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2)O)C(=O)C=1 |&1:18,21,23,25,r| |
| Hazard Information | Back Directory | [Chemical Properties]
Soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Dracocephalum moldavica L. | [Uses]
Tilianin has lipid-lowering and anti-inflammatory effects. | [Biological Activity]
Tilianin is an active flavonoid glycoside, widely present in a variety of medicinal plants, with antihypertensive, myocardial protection, antidiabetic, hypolipidemic, anti-inflammatory, antioxidant and other effects. | [in vitro]
Tilianin (10 μM, 20 μM) reduced secretion of LPS (1 μg/mL)-induced proinflammatory cytokine in RAW264.7 macrophage cell.
< /b> | [target]
5-HT Receptor | GABA Receptor | ATPase | NO | NOS | Caspase | Bcl-2/Bax | Potassium Channel | P-gp |
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