| Identification | Back Directory | [Name]
ACACETIN-7-GLUCOSIDE | [CAS]
4291-60-5 | [Synonyms]
TILIANIN
Astroside
Moldavoside
leptomerine
ACACETIN-7-GLUCOSIDE
Acacetin 7-O-glucoside
ACACETIN-7-GLUCOSIDE USP/EP/BP
Apigenin-7-O-beta-D-glucopyranoside-4'-O-methyl ether
7-(β-D-Glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)- | [Molecular Formula]
C22H22O10 | [MDL Number]
MFCD00238695 | [MOL File]
4291-60-5.mol | [Molecular Weight]
446.4 |
| Chemical Properties | Back Directory | [Melting point ]
260-262℃ | [Boiling point ]
754.9±60.0 °C(Predicted) | [density ]
1.545±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO | [form ]
powder | [pka]
6.11±0.40(Predicted) | [color ]
White-yellowish | [InChIKey]
NLZCOTZRUWYPTP-KWEUGPCZNA-N | [SMILES]
C1(C2=CC=C(OC)C=C2)OC2=C(C(=CC(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2)O)C(=O)C=1 |&1:18,21,23,25,r| |
| Hazard Information | Back Directory | [Chemical Properties]
Soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Dracocephalum moldavica L. | [Uses]
Tilianin has lipid-lowering and anti-inflammatory effects. | [Biological Activity]
Tilianin is an active flavonoid glycoside, widely present in a variety of medicinal plants, with antihypertensive, myocardial protection, antidiabetic, hypolipidemic, anti-inflammatory, antioxidant and other effects. | [Synthesis]
Since the chemical constituents of Fragrant Green Orchid Seed (Seed) have not been reported in the literature, the present study was carried out to isolate the chemical constituents from the authentic Fragrant Green Orchid Seed identified. The powder of F | [in vitro]
Tilianin (10 μM, 20 μM) reduced secretion of LPS (1 μg/mL)-induced proinflammatory cytokine in RAW264.7 macrophage cell.
< /b> | [target]
5-HT Receptor | GABA Receptor | ATPase | NO | NOS | Caspase | Bcl-2/Bax | Potassium Channel | P-gp |
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