| Identification | Back Directory | [Name]
Nicotinamide hypoxanthine dinucleotide phosphate reduced tetrasodium salt | [CAS]
42934-87-2 | [Synonyms]
deamino nadph
DEAMINO NADPH TETRASODIUM SALT
nicotinamide hypoxanthine dinucleotide*phosphate
Deaminotriphosphopyridine nucleotide, reduced form
NICOTINAMIDE HYPOXANTHINE DINUCLEOTIDE*P HOSPHATE, R
DEAMINO TRIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM TETRASODIUM SALT
Deamino NADPH, Deaminotriphosphopyridine nucleotide, reduced form
Nicotinamide hypoxanthine dinucleotide phosphate reduced tetrasodium salt
NICOTINAMIDE HYPOXANTHINE DINUCLEOTIDE PHOSPHATE, REDUCED FORM TETRASODIUM SALT
Inosine 5'-(trihydrogendiphosphate), 2'-(dihydrogen phosphate), P'5'-ester with 1,4-dihydro-1-b-D-ribofuranosyl-3-pyridinecarboxamide(9CI)
Inosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'→5'-ester with 1,4-dihydro-1-β-D-ribofuranosyl-3-pyridinecarboxamide (9CI) | [Molecular Formula]
C21H29N6O18P3 | [MDL Number]
MFCD00057028 | [MOL File]
42934-87-2.mol | [Molecular Weight]
746.41 |
| Hazard Information | Back Directory | [Description]
Nicotinamide hypoxanthine dinucleotide phosphate reduced tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. Nicotinamide hypoxanthine dinucleotide phosphate reduced tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication. The demand for NADPH tetrasodium salt is particularly high in proliferating cancer cells, where it acts as a cofactor for the synthesis of nucleotides, proteins, and fatty acids. Nicotinamide hypoxanthine dinucleotide phosphate reduced tetrasodium salt is also essential for the neutralization of the dangerously high levels of reactive oxygen species (ROS) generated by increased metabolic activity. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis. | [References]
[1] F da Fonseca-Wollheim, et al. Which is the appropriate coenzyme for the measurement of ammonia with glutamate dehydrogenase? Eur J Clin Chem Clin Biochem. 1992 Sep;30(9):537-40. PMID:1457616 |
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