| Identification | Back Directory | [Name]
DEOXYSHIKONIN | [CAS]
43043-74-9 | [Synonyms]
Arnebin 7
NSC 179184
Arnebin VII
Deoxyalkannin
DEOXYSHIKONIN
Anhydroalkanin
5,8-DIHYDROXY-2-(4-METHYL-3-PENTENYL)-1,4-NAPHTHALENEDIONE | [Molecular Formula]
C16H16O4 | [MDL Number]
MFCD00144053 | [MOL File]
43043-74-9.mol | [Molecular Weight]
272.3 |
| Chemical Properties | Back Directory | [Melting point ]
91°C | [Boiling point ]
503.7±50.0 °C(Predicted) | [density ]
1.269±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
7.42±0.20(Predicted) | [color ]
Brown to reddish brown | [CAS DataBase Reference]
43043-74-9 |
| Hazard Information | Back Directory | [Uses]
Deoxyshikonincan be used as a natural pigment in cosmetics and printing and dyeing industries, and has great development and application prospects. | [Definition]
ChEBI:Deoxyshikonin is a hydroxy-1,4-naphthoquinone. | [in vivo]
Deoxyshikonin (20?mg/kg; intraperitoneal injection; every two days for 13 days) markedly suppresses the growth of xenograft tumours on day 5, 9 and 11 with 20?mg/kg[1].
| Animal Model: | Male BALB/c nude mice of 10-14?g with DLD-1 cells[1] | | Dosage: | 20?mg/kg | | Administration: | Intraperitoneal injection; every two days for a total of 13 days | | Result: | Markedly suppressed the growth of xenograft tumours on day 5, 9 and 11 with 20?mg/kg, while there were no significant changes in body weight of the mice.
|
| [IC 50]
HIF-1α; HIF-1β; PI3K | [storage]
4°C, protect from light |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
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| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
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