| Identification | Back Directory | [Name]
AZD-0837 | [CAS]
433937-93-0 | [Synonyms]
CS-633
AZD-0837
AZD-0837
(AZD0837
Atecegatran metoxil)
Atecegatran fexenetil
XSNMGLZVFNDDPW-ZWKOTPCHSA-N
Atecegatran fexinitil/AZD0837
2-Azetidinecarboxamide, 1-[(2R)-2-[3-chloro-5-(difluoromethoxy)phenyl]-2-hydroxyacetyl]-N-[[4-[imino(methoxyamino)methyl]phenyl]methyl]-, (2S)- | [Molecular Formula]
C22H23ClF2N4O5 | [MDL Number]
MFCD16038920 | [MOL File]
433937-93-0.mol | [Molecular Weight]
496.89 |
| Hazard Information | Back Directory | [Uses]
Atecegatran metoxil is a oral anticoagulant, which inhibits thrombin factor II and is used in thromboembolic disorders. In vivo, Atecegatran metoxil is converted to AR-H067637, a selective and reversible direct thrombin inhibitor. | [References]
[1] Lip GY, Rasmussen LH, Olsson SB, et al. Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a randomized dose-guiding, safety, and tolerability study of four doses of DOI:10.1093/eurheartj/ehp318
[2] Olsson SB, Rasmussen LH, Tveit A, et al. Safety and tolerability of an immediate-release formulation of theoral direct thrombin inhibitor AZD0837 in the prevention of stroke and systemic embolism in patients with atrial fibrillation. Thromb Haemost. 2010; DOI:10.1160/TH09-07-0509 |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
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Cckinase, Inc.
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+1 (732)236-3202 |
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www.cckinase.com |
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