ChemicalBook--->CAS DataBase List--->443747-52-2

443747-52-2

443747-52-2 Structure

443747-52-2 Structure
IdentificationBack Directory
[Name]

Benzoic acid, 3-[[4-(3-nitrophenyl)-2-thiazolyl]amino]-
[CAS]

443747-52-2
[Synonyms]

WAY-302713-A
3-((4-(3-Nitrophenyl)thiazol-2-yl)amino)benzoic acid
Benzoic acid, 3-[[4-(3-nitrophenyl)-2-thiazolyl]amino]-
[Molecular Formula]

C16H11N3O4S
[MOL File]

443747-52-2.mol
[Molecular Weight]

341.34
Chemical PropertiesBack Directory
[Boiling point ]

597.1±60.0 °C(Predicted)
[density ]

1.498±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

4.13±0.10(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

CK2α-IN-1 (compound 2) is a selective CK2α inhibitor (IC50=7.0 μM; Ki=1.6 μM) that exhibits a non-ATP-competitive mode of action. CK2α-IN-1 exhibits good potential for anticancer studies[1].
[References]

[1] Bestgen B, et al. 2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site. J Med Chem. 2019 Feb 28;62(4):1803-1816. DOI:10.1021/acs.jmedchem.8b01766
Spectrum DetailBack Directory
[Spectrum Detail]

Benzoic acid, 3-[[4-(3-nitrophenyl)-2-thiazolyl]amino]-(443747-52-2)1HNMR
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