| Identification | Back Directory | [Name]
Benzoic acid, 3-[[4-(3-nitrophenyl)-2-thiazolyl]amino]- | [CAS]
443747-52-2 | [Synonyms]
WAY-302713-A
3-((4-(3-Nitrophenyl)thiazol-2-yl)amino)benzoic acid
Benzoic acid, 3-[[4-(3-nitrophenyl)-2-thiazolyl]amino]- | [Molecular Formula]
C16H11N3O4S | [MOL File]
443747-52-2.mol | [Molecular Weight]
341.34 |
| Chemical Properties | Back Directory | [Boiling point ]
597.1±60.0 °C(Predicted) | [density ]
1.498±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.13±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
CK2α-IN-1 (compound 2) is a selective CK2α inhibitor (IC50=7.0 μM; Ki=1.6 μM) that exhibits a non-ATP-competitive mode of action. CK2α-IN-1 exhibits good potential for anticancer studies[1]. | [References]
[1] Bestgen B, et al. 2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site. J Med Chem. 2019 Feb 28;62(4):1803-1816. DOI:10.1021/acs.jmedchem.8b01766 |
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