| Identification | More | [Name]
3-FLUORO-4-METHOXYPHENYLACETIC ACID | [CAS]
452-14-2 | [Synonyms]
3-FLUORO-4-METHOXYPHENYLACETIC ACID
RARECHEM AL BO 1534
3-Fluoro-4-methyloxyphenylaceticacid
3-Fluoro-4-methoxyphenylacetic acid 98%
3-Fluoro-4-methoxyphenylaceticacid98%
2-(3-fluoro-4-methoxyphenyl)acetic acid | [Molecular Formula]
C9H9FO3 | [MDL Number]
MFCD00060353 | [Molecular Weight]
184.16 | [MOL File]
452-14-2.mol |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H318 | [Precautionary statements ]
P280-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2918290090 |
| Hazard Information | Back Directory | [Synthesis]
3-fluoro-4-methoxyphenylacetonitrile (42 g, 0.25 mol) was heated for 5 h with 32 g of potassium hydroxide solution in 120 mL of ethanol and 30 mL of water. After the distillation of ethanol, the residue was diluted with water to a volume of 175 mL. The solution was filtered over the charcoal, and the filtrate was acidified by 50 percent H2SO4. The resulting solid was filtered and dried, yielding 3-Fluoro-4-methoxyphenylacetic acid. | [References]
[1] Collection of Czechoslovak Chemical Communications, 1990, vol. 55, # 1, p. 296 - 306
[2] European Journal of Medicinal Chemistry, 2014, vol. 87, p. 508 - 518
[3] Monatshefte fuer Chemie, 1955, vol. 86, p. 511,515
[4] DRP/DRBP Org.Chem.,
[5] Chemische Berichte, 1952, vol. 85, p. 577,580 |
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